Lack of renal NHE1 exacerbates lithium-induced nephrogenic diabetes insipidus
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Aims: The sodium-hydrogen exchanger isoform 1 (NHE1) is important for transepithelial Na+/H+ transport, intracellular pH, and cell volume regulation. NHE1 also transports Li+, preferably compared to NHE3, and the lack of NHE3 doe... ...
