The effect of RNLS gene polymorphisms on preeclampsia susceptibility: a meta-analysis study [0.03%]
关于RNLS基因多态性与子痫前期易感性的关联：一项荟萃分析研究
Saeedeh Salimi,Abbas Mohammadpour-Gharehbagh,Mohaddeseh Hedayat et al.
Saeedeh Salimi et al.
Aim: The authors designed a meta-analysis to find a comprehensive result of the impact of RNLS polymorphisms on preeclampsia (PE) susceptibility. Methods: The online databases PubMed, Scopus, and Google Scholar were employed for the purpose...
Improving resource allocation in the precision medicine Era: a simulation-based approach using R [0.03%]
基于R的模拟方法在精准医学时代改善资源分配
Mohamed Kamal,Mohamed Nagy,Omneya Hassanain
Mohamed Kamal
The application of personalized medicine in developing countries is a major challenge, especially for those with poor economic status. A critical factor in improving the application of personalized medicine is the efficient allocation of re...
European survey: citizens' attitudes on personalized medicine, genetic testing and health data sharing - design and delivery [0.03%]
欧洲调查：关于个体化医学、基因检测和健康数据共享的公民态度——设计与实施
Francesco Andrea Causio,Flavia Beccia,Loes Lindiwe Kreeftenberg et al.
Francesco Andrea Causio et al.
In the transformative landscape of healthcare, personalized medicine emerges as a pivotal shift, harnessing genetic, environmental and lifestyle data to tailor medical treatments for enhanced outcomes and cost efficiency. Central to its suc...
Optimizing vancomycin therapeutic drug monitoring compliance in pediatric oncology: towards personalized medication management [0.03%]
儿科肿瘤学万古霉素治疗药物监测的优化：迈向个性化药物管理
Rewan Gamal Mohamed,Rania Saber,Mohamed Ali Hussein et al.
Rewan Gamal Mohamed et al.
Aim: Vancomycin, a crucial treatment for Gram-positive bacteria, necessitates therapeutic drug monitoring (TDM) to prevent treatment failures. We investigated the healthcare professional's compliance toward TDM of vancomycin recommendations...
Efficacy and tolerability of capmatinib in a very elderly patient with metastatic NSCLC harboring a MET exon 14 mutation [0.03%]
卡马替尼治疗携带MET外显子14跳跃突变的非常老年的转移性非小细胞肺癌患者的有效性和耐受性
Nicole Conci,Virginia Marchiori,Alessandro Di Federico et al.
Nicole Conci et al.
We report the case of an 87-year-old female patient who was diagnosed with metastatic non-small-cell lung cancer harboring MET exon 14 skipping mutation (MET ex14) and PD-L1 expression of 60%. A first-line treatment with atezolizumab was st...
Preliminary study of identified novel susceptibility loci for HAPE risk in a Chinese male Han population [0.03%]
针对藏族高海拔居民的HAPE易感新位点的功能初探研究
Beibei Zhao,Changchun Liu,Yijin Qi et al.
Beibei Zhao et al.
High altitude pulmonary edema (HAPE) is a life-threatening form of non-cardiogenic pulmonary edema. In recent years, association studies have become the main method for identifying HAPE genetic loci. A genome-wide association study (GWAS) o...
Usefulness of vancomycin treatment individualization via Bayesian algorithms: a 5-year study in critical patients [0.03%]
基于贝叶斯算法的万古霉素治疗个体化用药的研究——一项为期五年的危重患者研究
Salvador Cabrera Figueroa,Diego Salazar Pincheira,Claudio Bustos Navarrete et al.
Salvador Cabrera Figueroa et al.
Aim: Compare two vancomycin dosing strategies in critical patients with methicillin-resistant Staphylococcus aureus (MRSA) infections, considering the heterogeneity of the dosing regimens administered and their implications for toxicity and...
Observational Study
Personalized medicine. 2024;21(4):243-255. DOI:10.1080/17410541.2024.2365616 2024
Gene detection of VDR BsmI locus and its approteins, genes and growthplication in rational drug use in patients with osteoporosis [0.03%]
维生素D受体BsmI位点基因检测及其在骨质疏松症合理用药中的应用
Yu Huang,Nan Qiu,Yunna Wang et al.
Yu Huang et al.
Aim: This paper determines the polymorphism distribution of the VDR BsmI gene in 350 patients and provides medication recommendations for osteoporosis based on detection results. Materials & methods: Chi-square tests compared genotype and a...
The prognostic potential of long noncoding RNA XIST in cardiovascular diseases: a review [0.03%]
长非编码RNA XIST在心血管疾病预后中的潜力：综述
Habib Haybar,Ehsan Sarbazjoda,Daryush Purrahman et al.
Habib Haybar et al.
There is a significant mortality rate associated with cardiovascular disease despite advances in treatment. long Non-coding RNAs (lncRNAs) play a critical role in many biological processes and their dysregulation is associated with a wide r...
Incidence of statin-associated muscle symptoms in patients taking statins with RYR1 or CACNA1S variants [0.03%]
RYR1或CACNA1S基因变异的他汀类药物使用者的肌病发生率
Natasha J Petry,Amanda Massmann,Megan Bell et al.
Natasha J Petry et al.
Background: Statins are commonly used medications. Variants in SLCO1B1, CYP2C9, and ABCG2 are known predictors of muscle effects when taking statins. More exploratory genes include RYR1 and CACNA1S, which can also be associated with disease...