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Incidence of statin-associated muscle symptoms in patients taking statins with RYR1 or CACNA1S variants

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Background: Statins are commonly used medications. Variants in SLCO1B1, CYP2C9, and ABCG2 are known predictors of muscle effects when taking statins. More exploratory genes include RYR1 and CACNA1S, which can also be associated with disease conditions. Methods... ...