Compassionate Access Drug Use for Solid Organ Malignancies in a Metropolitan Cancer Centre in Australia Between 2017 and 2024 [0.03%]
2017年至2024年澳大利亚某癌症中心实体器官恶性肿瘤同情用药的使用情况
Yun San Chong,Nicholas Yeo,Grace Redmayne et al.
Yun San Chong et al.
Introduction: The Pharmaceutical Benefits Scheme (PBS) provides affordable access to cancer treatments in Australia. Not all cancer treatments are available on the PBS. Access to non-PBS-listed cancer treatments can occur...
Investigation of the Expression of Bcl-2 Interacting Protein 3 (BNIP3) and Its Molecular Association With Tumor Hypoxia and Immune Response in Breast Cancer [0.03%]
乳腺癌中BNIP3表达及其与肿瘤低氧和免疫反应分子关联的调查研究
Khalidha Noordeen,B S Lakshmi
Khalidha Noordeen
Background: BNIP3 is a crucial gene involved in mitophagy that modulates mitochondrial and cellular homeostasis. However, there is limited research examining its biological regulation. The current study investigates the e...
Qilian Mixture as an Adjunct Treatment During Gefitinib Therapy in Lung Adenocarcinoma Patients: A Randomized Controlled Clinical Trial With Mechanism Exploration [0.03%]
祁连复方辅治吉非替尼肺癌的临床试验及机制探讨研究
Zhaoshui Li,Ting Jiang,Xin Zheng
Zhaoshui Li
Aim: Targeted therapy is recommended for lung adenocarcinoma patients with epidermal growth factor receptor (EGFR) mutations. We aimed to investigate clinical efficacy and safety, as well as the potential underlying mecha...
A Japanese Multicenter Database Study of Retroperitoneal Sarcoma: Outcomes of Patients Receiving Eribulin Therapy [0.03%]
一项日本多中心数据库的后腹膜肉瘤研究——埃里布林治疗患者的预后情况
Makito Miyake,Yuki Oda,Nobutaka Nishimura et al.
Makito Miyake et al.
Aim: Clinical evidence on disease characteristics and outcomes of retroperitoneal sarcoma (RPS) remains limited. Although eribulin was approved for soft tissue sarcomas in Japan in 2016, real-world data on its use for adv...
Pattern of Metastasis as a Risk Factor for Brain Metastasis in Patients With Breast Cancer: A Time-Dependent Cox Regression [0.03%]
转移模式作为乳腺癌患者脑转移风险因素的影响：时间依赖的Cox回归分析
Eunbin Park,Jung Ho Park,Hong Kyu Lee et al.
Eunbin Park et al.
Aim: Brain metastasis is associated with poor prognosis in patients with breast cancer. Conventional predictive models rely on fixed baseline characteristics and provide limited clinical utility. We aimed to analyze the f...
Assessment of Outcomes of Palliative Radiologic Percutaneous Biliary Drainage and Metal Stenting in Adult Patients With Malignant Hilar Biliary Obstruction [0.03%]
成人恶性肝门胆管梗阻患者经皮胆道引流和金属支架置入的姑息性放射学结果评估
Raja Chaganti,Milad Ghasemzadeh,Matthew Wong et al.
Raja Chaganti et al.
Objective: Review outcomes for patients undergoing biliary drainage and stenting via percutaneous transhepatic cholangiography, drainage, and stenting (PTCDS) for malignant hilar biliary obstruction secondary to hepatopan...
Benchmarked Colorectal Cancer Outcomes in a Metropolitan Hospital: A 5-Year Review [0.03%]
城市医院结直肠癌治疗效果的五年回顾及对照研究
Jialin Du,Vincent Wang,Basil D&#x;Souza et al.
Jialin Du et al.
Introduction: Colorectal cancer (CRC) remains a major contributor to cancer-related mortality worldwide, with survival influenced by many prognostic factors. This study aims to evaluate survival outcomes and prognostic fa...
Impact of Metformin and Diabetes on Tumor Response to Total Neoadjuvant Therapy in Advanced Rectal Cancer: A Multicenter Retrospective Cohort Study [0.03%]
二甲双胍和糖尿病对晚期直肠癌综合新辅助治疗肿瘤反应影响的多中心回顾队列研究
Sergei Bedrikovetski,Mahima Raju,Tracy Fitzsimmons et al.
Sergei Bedrikovetski et al.
Aim: Diabetes mellitus (DM) is associated with impaired response to neoadjuvant chemoradiotherapy in rectal cancer. Metformin may enhance treatment response by improving tumor oxygenation and inhibiting cell growth and pr...
β-Cyclodextrin-Coated Paclitaxel-Loaded Mesoporous Silica Nanocarriers: Mechanistic Insights Into Sustained Release, Enhanced Cellular Uptake, and Apoptosis in MCF-7 Breast Cancer Cells [0.03%]
β-环糊精包覆的载紫杉醇介孔硅纳米载体：持续释放、细胞摄取增强及MCF-7乳腺癌细胞凋亡的机制研究
Dilpreet Singh
Dilpreet Singh
The present study aimed to develop and evaluate β-cyclodextrin (β-CD)-coated mesoporous silica nanoparticles (MSNs) for the controlled delivery of paclitaxel (PTX) to improve its aqueous solubility, stability, and anticancer efficacy. MSN...
Evaluating Gentian Violet as a Low-Cost Alternative for Sentinel Lymph Node Biopsy in Breast Cancer: A Single-Center Retrospective Study [0.03%]
单中心回顾性研究评估毛地黄紫作为乳腺癌哨点淋巴结活检的低成本替代品的价值
Mehwish Mooghal,Zakia Madad Ali,Lubna Saleem et al.
Mehwish Mooghal et al.
Background: Sentinel lymph node biopsy (SLNB) reduces morbidity in breast cancer (BC) surgery compared to axillary lymph node dissection. Standard tracers such as vital blue dye (VBD), methylene blue (MB), and radioisotop...