Good's Syndrome Complicated with COVID-19 and Recurrent Pulmonary Infections: A Case Report [0.03%]
良好综合症并发COVID-19和反复肺部感染的病例报告
Wenjuan Xia,Mengqi Wu,Fang He
Wenjuan Xia
Good's syndrome (GS), a rare immunodeficiency disorder characterized by thymoma and hypogammaglobulinemia, presents diagnostic and therapeutic challenges due to recurrent infections. We report a 53-year-old male farmer with GS complicated b...
The Coexistence of Asthma and Common Variable Immunodeficiency in a Patient with TNFRSF13B Gene Mutation [0.03%]
TNFRSF13B基因突变患者哮喘与常见变异型免疫缺陷病并存的一例
Tayebeh Ranjbarnejad,Mansoor Salehi,Hassan Abolhassani et al.
Tayebeh Ranjbarnejad et al.
Common variable immunodeficiency disorder (CVID) is the most prevalent primary immunodeficiency in adults. Pathogenic mutations of the TNFRSF13B gene were identified in CVID patients and associated with autoimmunity and lymphoproliferation....
Alterations in Apoptotic Cell Populations, Protein Markers, and Gene Expression Patterns in Rats with Sulfur Mustard-induced Pulmonary Injuries [0.03%]
芥气致大鼠肺损伤后凋亡细胞群体、蛋白标志物及基因表达模式的改变研究
Tao Liu,Na Zhang,Xin Shu et al.
Tao Liu et al.
Sulfur mustard (SM) is a potent chemical warfare agent that causes severe cutaneous, ocular, and pulmonary injuries, with respiratory tract damage being the most life-threatening. Despite its well-documented toxicity, the cellular mechanism...
Dual Blockade of PD-L1 and AXL: A Novel Immunotherapeutic Approach for Ovarian and Cervical Cancer [0.03%]
PD-L1和AXL双重阻断：卵巢癌和宫颈癌免疫治疗的新方法
Hossein Rahavi,Ahmad Najafi,Hossein Asgarian-Omran et al.
Hossein Rahavi et al.
Tumor microenvironment modulators have produced durable effects in cancer treatment. Targeting immune checkpoint receptors, such as PD-L1, has demonstrated efficacy in eliciting antitumor responses. However, resistance to immune checkpoint ...
Role of METTL3 Protein in Asthma: Insights from Transcriptomic Profiling and Molecular Docking Analysis [0.03%]
METTL3蛋白在哮喘中的作用：来自转录组分析和分子对接的见解
Kaichong Jiang,Qiao Li,Ling Duan et al.
Kaichong Jiang et al.
Asthma is a chronic inflammatory disease characterized byimmune dysregulation. This study aimed to perform unbiased analysis of transcriptomic data to identify differentially expressed m6A-related genes in asthma, with a focus on exploring ...
The Value of Anti-Drug Antibody Detection in Discriminating Patients from Healthy Controls and Predicting the Gross Motor Functional State in Patients with Pompe Disease [0.03%]
测定抗药物抗体在Pompe病患者与健康对照者之间鉴别的价值及预测患者的粗大运动功能状况
Solmaz Aziz-Ahari,Mahdi Aminian,Aliasghar Rahimian et al.
Solmaz Aziz-Ahari et al.
Anti-recombinant human acid α-glucosidase (anti-rhGAA) antibody formation is a major challenge in patients with Pompe disease receiving enzyme replacement therapy (ERT). The clinical significance of these antibodies and their detection met...
Integration of Cervical Length, Inflammatory Marker, and Vaginal Biomarkers (PAMG-1 and fFN) in the Diagnosis of Threatened Preterm Labor [0.03%]
宫颈长度、炎症标志物及阴道生物标志物(PAMG-1和fFN)在诊断胎膜早破中的联合应用研究
Jianfeng Lu,Juefei Lu,Xiaoli Zhang et al.
Jianfeng Lu et al.
The aim of this research was to evaluate the diagnostic efficacy of integrating cervical length (CL), interleukin-6 (IL-6), placental alpha microglobulin-1 (PAMG-1), and fetal fibronectin (fFN) in predicting preterm birth among pregnant wom...
Analysis of the Diagnostic Value of Peripheral Blood Indicators for Acute Pyelonephritis and the Influencing Factors of Poor Prognosis [0.03%]
急性肾盂肾炎外周血标志物诊断价值分析及不良预后的的影响因素分析
Haiyang Qian,Danni Zhou,Hao Wang
Haiyang Qian
This study explored the diagnostic value of peripheral blood indices for acute pyelonephritis (APN) and the factors influencing poor prognosis. A total of 118 patients with APN admitted to our hospital from January 2022 to June 2024 were re...
Association of Systemic Immune Inflammation Index and Pan-immune Inflammation Value with Prognosis in Idiopathic Membranous Nephropathy [0.03%]
系统免疫炎症指数和泛免疫炎症值与特发性膜性肾病预后的关系研究
Fangqian Liang,Yuyang Yang,Yao Sun et al.
Fangqian Liang et al.
Idiopathic membranous nephropathy (IMN) presents a heterogeneous clinical course, with approximately 30% to 40% of patients experiencing spontaneous remission, while others respond poorly to treatment. This study aims to identify reliable b...
Assessment of Rigid Nasopharyngoscopy Beyond the Nasal Cavity in Diagnosis of Immune-mediated Nasopharyngeal Allergic Diseases [0.03%]
rigid鼻咽镜检查在免疫性鼻咽过敏性疾病诊断中价值的评估
Hongbo Wang,Panru Zhu,Jiangqiao Geng et al.
Hongbo Wang et al.
Rigid nasopharyngoscopy is a valuable diagnostic method for immune-mediated allergy conditions, particularly for children aged≤6 years. In addition to evaluating the structural characteristics of the nasal cavity, the procedure also reveal...