NK-cell-derived exosomes exert antitumor potency via miR-140/XYLT1/HSPG2 axis [0.03%]
自然杀伤细胞源性外泌体通过miR-140/XYLT1/HSPG2轴发挥抗肿瘤作用
Dingru Li,Zerui Chen,Herong Liang et al.
Dingru Li et al.
Hedgehog pathway activity downstream of Smoothened is regulated specifically by basal ciliary PKA [0.03%]
基底纤毛PKA特异性调控Smoothened下游的Hh信号通路活性
Hongyu Zhang,Shujing Chen,Zhuoya Huang et al.
Hongyu Zhang et al.
Restoration of lysosomal membrane integrity in cell models of Pompe disease depends on fatty acid synthase and its product palmitic acid [0.03%]
基于庞培病的细胞模型的溶酶体膜修复依赖于脂肪酸合酶及其产物棕榈酸
Edouard Le Guillou,Arianna Segaloni,Alexis Gadault et al.
Edouard Le Guillou et al.
A tRNA-derived fragment tRF3019a promotes LUAD metastasis by stabilizing hnRNPK and enhancing MYH11 expression [0.03%]
tRF3019a通过稳定hnRNPK并增强MYH11表达促进LUAD转移
Xin Li,Weifang Cui,Zhangjie Wang et al.
Xin Li et al.
EIF4A3-induced circUBAC2 promotes lung cancer progression via regulation of the Hippo signaling pathway [0.03%]
circUBAC2诱导的EIP4A3通过调节Hippo信号通路促进肺癌进展
Fan Meng,Xiaokang Zhang,Xinlin Wang et al.
Fan Meng et al.
Integrated analysis of single-cell RNA sequencing, transcriptomics, and thermal proteome profiling identifies PLCG1 as the therapeutic target of isopimpinellin in treating rheumatoid arthritis [0.03%]
单细胞RNA测序、转录组和热蛋白组综合分析确定PLCG1为异秦皮啶治疗类风湿性关节炎的靶点
Huantian Cui,Ning Wang,Feitian Min et al.
Huantian Cui et al.
ADAM9 in tumor biology: molecular functions, clinical implications, and therapeutic targeting [0.03%]
ADAM9在肿瘤生物学中的分子功能、临床意义及治疗靶向性研究
Kuo-Hao Ho,Chao-Jung Wu,Yi-Chieh Yang et al.
Kuo-Hao Ho et al.
A disintegrin and metalloproteinase 9 (ADAM9), a member of the ADAM family, is expressed across multiple organs and is crucial to multiple physiological processes. Increasing evidence implicates ADAM9 in cancer progression through extracell...
DYRK2 drives renal fibrosis through CDK1-dependent G2/M phase dysregulation in tubular epithelial cells [0.03%]
DYRK2通过依赖CDK1的近曲肾小管上皮细胞G2/M期失调驱动肾纤维化
Fang Bai,Chunjie Wang,Sha Wang et al.
Fang Bai et al.
Ribbon constrains dendritic pruning via actin scaffolding and exocyst complex [0.03%]
丝带通过肌动蛋白支架和分泌衔接复合体限制树突修剪
Wanting Wang,Su Wang,Yuhao Yuan et al.
Wanting Wang et al.
Palmitoylation-dependent regulation of innate and adaptive immunity: molecular insights and translational opportunities [0.03%]
棕榈酰化调节固有免疫和适应性免疫：分子见解与转化机遇
Binhui Zhou,Bowen Zhang,Yingcheng Qi et al.
Binhui Zhou et al.