Remote neuromuscular electrical stimulation upregulates MDK to enhance macrophage efferocytosis via LRP1 in wound healing [0.03%]
远程神经肌肉电刺激通过LRP1上调MDK以增强巨噬细胞的凋亡细胞吞噬作用从而促进伤口愈合
Lijuan Zong,Chong Liu,Li Zhang et al.
Lijuan Zong et al.
Neuromuscular electrical stimulation (NMES) is a well-established therapeutic approach for chronic wounds. Conventionally, NMES involves direct electrode contact with wounds or adjacent healthy skin; however, it is limited by the need for w...
Probiotic Akkermansia muciniphila alleviates acute kidney injury by protecting the intestinal barrier and modulating gut microbiota and metabolites [0.03%]
乳酸菌Akkermansia muciniphila通过保护肠屏障和调节肠道微生物群和代谢物来缓解急性肾损伤
Juan Ni,Zhan Yang,Xuewei Sun et al.
Juan Ni et al.
Acute kidney injury (AKI) is a critical condition with limited effective therapies. Akkermansia muciniphila ( A. muciniphila) is a probiotic with multiple beneficial effects, including epithelial cell tight junctions regulation. Since renal...
A healthy lifestyle pattern and mortality risk in patients of type 2 diabetes mellitus: a prospective cohort study in China [0.03%]
健康生活方式与2型糖尿病患者的死亡风险：一项前瞻性队列研究
Hao Yu,Xinyi Liu,Xueni Cheng et al.
Hao Yu et al.
This study aimed to evaluate the association of a healthy lifestyle pattern with mortality risk among patients with type 2 diabetes mellitus (T2DM). Data were derived from a prospective cohort enrolling 13,776 Chinese patients with T2DM. A ...
RAF1 in AgRP neurons involved in the regulation of energy metabolism via the MAPK signaling pathway [0.03%]
RAF1通过MAPK信号通路参与调控下丘脑AgRP神经元的能量代谢
Yuqian Chen,Lianci Ren,Xinyi Xu et al.
Yuqian Chen et al.
V-raf-leukemia viral oncogene 1(RAF1), a serine/threonine protein kinase, is universally acknowledged to play a crucial role in tumorigenesis and cell development. However, the specific role of hypothalamic RAF1 in regulating energy metabol...
Monocyte to HDL cholesterol ratio predicts obesity-associated cardiac dysfunction [0.03%]
单核细胞与高密度脂蛋白胆固醇比率可预测肥胖相关心脏功能障碍
Chunsheng Zhao,Jinting Liu,Jiaqi Zhao et al.
Chunsheng Zhao et al.
As prevalence of obesity increases dramatically, obesity-associated cardiac dysfunction constitutes a huge challenge to human health. This study aims to find more useful lipid/inflammatory markers to predict the risk of obesity-associated c...
The effect and toxicity profile of consolidative or salvage thoracic radiotherapy following chemoimmunotherapy in patients with extensive stage small cell lung cancer [0.03%]
广泛期小细胞肺癌化疗免疫治疗后巩固或补救性胸部放疗的效果及毒性谱特征分析
Ruo-Zhou Sun,Dan Zong,Xin Chen et al.
Ruo-Zhou Sun et al.
This study evaluated the efficacy and safety of thoracic radiotherapy (TRT) after first-line chemotherapy or chemoimmunotherapy in patients with extensive-stage small cell lung cancer (ES-SCLC), focusing on the impact of different TRT timin...
LAG3 facilitates MHCII trogocytosis with the assistance of ER-PM junction [0.03%]
LAG3通过ER-PM连接辅助促进MHCII分子转移摄取
Zibin Wang,Wene Zhao,Wen Liu et al.
Zibin Wang et al.
DEC1 promotes breast cancer bone metastasis through transcriptional activation of CXCR4 [0.03%]
DEC1通过转录激活CXCR4促进乳腺癌骨转移
Ying Huo,Kaiao Chen,Zhiyi Qiang et al.
Ying Huo et al.
Bone metastasis is the primary cause of mortality in breast cancer (BC) patients. This study elucidates the functional role of DEC1 (differentiated embryonic chondrocyte expressed gene 1) in promoting BC bone metastasis. Analysis of patient...
Phenotype and genotype analyses of 21 Chinese patients with Dent disease [0.03%]
21例中国Dent病患者的表型和基因型分析
Ruochen Che,Yuwen Cai,Wei Zhou et al.
Ruochen Che et al.
Dent disease is a rare X-linked recessively inherited renal tubulopathy, caused by variants in CLCN5 (Dent disease type 1, DD1) and OCRL (Dent disease type 2, DD2) and characterized by low molecular weight proteinuria, hypercalciuria, micro...
Association between serum 25(OH)D and cancer in adults with psoriasis: a cross-sectional study [0.03%]
成人银屑病患者血清25(OH)D与癌症的关联：一项横断面研究
Lingquan Deng,Yamei Gao,Chenxingyue Zhang et al.
Lingquan Deng et al.