Marine Bioactive Components and Chronic Neuroinflammation: Focus on Neurodegenerative Disease [0.03%]
海洋生物活性成分与慢性神经炎症：聚焦神经系统退行性疾病
Elda Favari,Cinzia Parolini
Elda Favari
Advances in neuroscience, immunology, and neuroimmunology have revealed that the nervous and immune systems form a bidirectional integrated network, ranging from regulating inflammation to directing stress responses, pivotal for the mainten...
A Marine-Derived Sterol, Ergosterol, Mitigates UVB-Induced Skin Photodamage via Dual Inhibition of NF-κB and MAPK Signaling [0.03%]
海洋甾醇 Ergosterol通过抑制NF-κB和MAPK信号减轻UVB引起的皮肤光损伤
Junming Zhang,Jiangming Zhong,Yi Li et al.
Junming Zhang et al.
Background: Ultraviolet B (UVB) radiation induces oxidative stress, inflammation, and collagen degradation in skin, leading to photodamage. Ergosterol (ERG)-a sterol widely distributed in fungi and algae, including numero...
Botryocladia leptopoda Extracts Promote Wound Healing Ability via Antioxidant and Anti-Inflammatory Activities and Regulation of MMP/TIMP Expression [0.03%]
抗氧化和抗炎作用及调控基质金属蛋白酶/基质金属蛋白酶抑制剂表达促进伤口愈合能力的Botryocladia leptopoda提取物研究
Shin-Ping Lin,Tsung-Kai Yi,Yi-Feng Kao et al.
Shin-Ping Lin et al.
Wound healing is a complex process involving coordinated actions of multiple cell types. Therefore, when developing therapeutics to promote wound healing, it is essential to consider the synergistic contributions of various cells at differe...
Characterization and Valorization of the Microalgal Co-Product Spirugrass®: Protein Profile, Iron Speciation, and Potential Use as a Supplement for Honeybees [0.03%]
微藻副产物Spirugrass的表征与增值：蛋白质谱、铁形态及作为蜜蜂补充饲料的潜在用途
Thomas Dalmonte,Cecilia Rudelli,Daniele Alberoni et al.
Thomas Dalmonte et al.
Microalgae are used as dietary supplements for humans and animals, due to their excellent nutritional profile. This research aims to characterize Spirugrass®, a co-product obtained after the extraction of phycocyanin from Limnospira platen...
Dictyostelium discoideum as a Platform to Assess the Cytotoxicity of Marine Algal Extracts: The Case of Glossophora kunthii [0.03%]
模式生物Dictyostelium discoideum评估海洋藻类提取物毒性的研究——以Glossophora kunthii为例
Sheyla J Figueroa-Valencia,Marcos Hernández,Grover Castañeta et al.
Sheyla J Figueroa-Valencia et al.
The social amoeba Dictyostelium discoideum is a versatile biological model widely used in drug discovery and studying cellular stress responses. However, its application for cytotoxicity evaluation of natural products, particularly algal-de...
An Astaxanthin-Binding Ependymin-Related Purple Protein Responsible for the Coloration of a Marine Purple Sponge, Haliclona sp [0.03%]
一种虾青素结合蛋白类紫蛋白负责海洋紫色管底海绵Haliclona sp.的色彩化作用
Takayuki Kaneko,Tomomi Asano,Shinji Kawasaki
Takayuki Kaneko
Although marine sponges display strikingly diverse colors, the molecular basis of this color diversity remains largely unknown. Recently, the blue coloration of Haliclona sp. was attributed to a water-soluble carotenoprotein that binds oran...
Structure Meets Function: Dissecting Fucoxanthin's Bioactive Architecture [0.03%]
结构与功能的结合：解构褐藻素的生物活性架构
Patrícia Nogueira,Victória Bombarda-Rocha,Rita Tavares-Henriques et al.
Patrícia Nogueira et al.
Fucoxanthin (Fx), a marine xanthophyll carotenoid, has attracted considerable scientific attention due to its wide-ranging biological activities, including antioxidant, anti-inflammatory, anti-obesity, and anticancer effects. Despite its su...
Daniela Dimitrova,Gabriela Kehayova,Simeonka Dimitrova et al.
Daniela Dimitrova et al.
Alzheimer's disease continues to be one of the most urgent neurodegenerative conditions, with acetylcholinesterase (AChE) inhibitors serving as a fundamental component of contemporary treatment approaches. Growing evidence underscores that ...
Michi Yao,Hafiz Muhammad Usama Shaheen,Chen Zuo et al.
Michi Yao et al.
Global agricultural production is challenging due to climate change and a number of phyto-pathogenic organisms and pests that pose a significant threat to both crop growth and productivity. The growing resistance of pests and diseases to sy...
Huayan Xu,Yuyue Li,Yuecheng Fang et al.
Huayan Xu et al.
Our previously discovered marine natural products, peniterphenyls A and E, exhibit superior anti-herpes simplex virus 1/2 (HSV 1/2) activity, probably via interference with virus adsorption and membrane fusion to host cells. Their clear mec...