Equinatoxin II: How a Cationic Pore-Forming Sea Anemone Toxin Drives Nodal Swelling of Myelinated Nerve Fibers [0.03%]
equinatoxin II：带正电的孔形成海葵毒素如何驱动髓鞘神经纤维结节肿胩
Evelyne Benoit,Robert Frangež,Gilles Ouanounou et al.
Evelyne Benoit et al.
This study was performed to elucidate the mechanism underpinning the nodal swelling induced by equinatoxin II (EqtII), a cation-selective pore-forming toxin derived from the sea anemone Actinia equina. Experiments were conducted using frog ...
Fucoidan Oligosaccharides from Kjellmaniella crassifolia Ameliorate Ulcerative Colitis by Regulating the TLR4 and NF-κB Signaling Pathway and Modulating Gut Microbiota [0.03%]
海带多糖寡糖通过调节Tlr4和NF-κB信号通路及调控肠道菌群治疗溃疡性结肠炎
Zhiying Xu,Zheyu Jia,Liu Li et al.
Zhiying Xu et al.
Ulcerative colitis (UC) is a form of inflammatory bowel disease (IBD), which is marked by severe abdominal pain, weight loss, perianal bleeding, and diarrhea. This study successfully isolated and purified four low-molecular-weight fucoidan ...
Algae-Derived Bioactives Reprogram the Gut-SIRT1-Kisspeptin Axis in Polycystic Ovary Syndrome [0.03%]
藻类活性物质调节多囊卵巢综合征的肠道-SIRT1-亲吻肽轴
Arifa Mustika,Era Gorica,Dante Saksono Harbuwono et al.
Arifa Mustika et al.
Polycystic ovary syndrome (PCOS) is increasingly recognized as a complex, multi-system disorder involving interactions among metabolic dysfunction, chronic low-grade inflammation, and neuroendocrine dysregulation, rather than a condition co...
Enhancing the Recovery of Antioxidant Compounds from Microalgae-Cyanobacteria Consortia Through Alcalase Hydrolysis: A Focus on Bioactive Peptides [0.03%]
通过碱性蛋白酶水解增强微藻-蓝细菌共生体系中抗氧化化合物的提取率：生物活性肽的研究焦点
Blanca Pardo de Donlebún,Rocío Del Álamo,Pilar Águila-Carricondo et al.
Blanca Pardo de Donlebún et al.
Microalgae and cyanobacteria represent an emerging and sustainable source of bioactive compounds for the food, cosmeceutical, and pharmaceutical sectors. In this study, the potential of two microalgae-cyanobacteria consortia, consortium 1 (...
Evaluation of Formulation-Dependent Antimicrobial Activity and Plant Compatibility of Chitosan-Based Silver Nanoparticles [0.03%]
基于壳聚糖的银纳米颗粒的配方依赖性抗菌活性及植物相容性的评价研究
Ahmed Hosney,Neringa Matelionienė,Donata Drapanauskaitė et al.
Ahmed Hosney et al.
Chitosan-based silver nanoparticles (Ch-AgNPs) are emerging as promising antimicrobial materials with potential applications in crop protection. This study evaluated the formulation-dependent antimicrobial activity and plant compatibility o...
From Sea to Cell: Ascophyllum nodosum and Fucus vesiculosus Extracts Attenuate NF-κB-Mediated Inflammation and Protect Intestinal Barrier Integrity-A Comprehensive Analysis Applying In Vitro and In Vivo Models [0.03%]
从海洋到细胞：海带（Ascophyllum nodosum）和泡叶藻（Fucus vesiculosus）提取物通过体内体外模型综合分析NF-κB介导的炎症缓解和肠道屏障完整性保护作用
Lea Karlsberger,Nadiia Sadova,Mara Heckmann et al.
Lea Karlsberger et al.
The restriction of antimicrobial growth promoters in livestock production has intensified the search for nutritional strategies that support intestinal health while modulating inflammatory processes. Chronic or dysregulated inflammation can...
Receptor Binding, Functional Activity, and Cell Viability Assessment of Novel Marine-Based Hybrid Peptides from Raja porosa [0.03%]
基于新型海洋杂化肽Raja porosa的受体结合、功能活性和细胞活力评估
Marta Bauer,Łukasz Szeleszczuk,Bharath Kumar Velmurugan et al.
Marta Bauer et al.
The hybrid approach remains a compelling strategy for designing molecules that combine enhanced biological activity with a favorable safety profile. Marine peptides, in particular, have attracted significant attention due to their well-docu...
Identification, Screening and Mechanism Analysis of Anti-Parkinson's Disease Peptides from Rapana venosa Protein Hydrolysates [0.03%]
从魁蛤蛋白酶解物中鉴定、筛选及分析抗帕金森病肽的效果和机制
Qingzhong Wang,Shuqin Shao,Yizhuo Wang et al.
Qingzhong Wang et al.
At present, there is still a lack of effective treatments to slow the progression of Parkinson's disease. Naturally derived active substances, valued for their safety and multi-target potential, have become an important direction in anti-PD...
Laminaran Attenuates NaCl-Induced Cytotoxicity via ROS Scavenging and Prevents Alteration of Cellular Elastic Modulus [0.03%]
通过ROS清除作用减轻NaCl诱导的细胞毒性的石莼糖醛酸多糖并防止细胞弹性模量的变化
Hiromi Kurokawa,Atsushi Taninaka,Hirofumi Matsui et al.
Hiromi Kurokawa et al.
Salt is essential for the maintenance of cellular homeostasis and transmission of nerve impulses. However, excessive salt intake (especially NaCl) causes hypertension and neoplasms and is associated with neoplasms, including esophageal and ...
Valorization of Chum Salmon (Oncorhynchus keta) Processing By-Products: High-Value Functional Food Ingredients for Skin Health [0.03%]
狗鱼大马哈鱼（ Oncorhynchus keta）加工副产物的高价值功能食品衍生物作为护肤原料的研究
Wook-Chul Kim,Yun-Su Lee,Seo-Rin Jung et al.
Wook-Chul Kim et al.
The strategic recycling of fish processing byproducts as functional materials has attracted increasing attention for sustainable development and human health. In this study, we investigated the dermatological impact of chum salmon (Oncorhyn...