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Toxicity Assessment of 6-Deoxytetrodotoxin by Mouse Bioassay and Its Distribution in Pufferfish

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Tetrodotoxin (TTX, 1) is a potent neurotoxin that occurs in a wide range of marine and terrestrial organisms. 6-DeoxyTTX (2) was isolated from pufferfish as a low-abundance TTX analogue. Although the toxicities of major TTX analogues have been investigated, th... ...