PFΔScreen - an open-source tool for automated PFAS feature prioritization in non-target HRMS data [0.03%]
PFΔScreen——一个用于非目标高分辨率质谱数据中PFAS特征优先级自动化的开源工具
Jonathan Zweigle,Boris Bugsel,Joel Fabregat-Palau et al.
Jonathan Zweigle et al.
Per- and polyfluoroalkyl substances (PFAS) are a huge group of anthropogenic chemicals with unique properties that are used in countless products and applications. Due to the high stability of their C-F bonds, PFAS or their transformation p...
Improved characterization of trastuzumab deruxtecan with PTCR and internal fragments implemented in middle-down MS workflows [0.03%]
基于PTCR和内部肽段的中端质谱分析方法在特鲁扎杜单抗表征中的应用研究
Corentin Beaumal,Evolène Deslignière,Hélène Diemer et al.
Corentin Beaumal et al.
Antibody-drug conjugates (ADCs) are highly complex proteins mainly due to the structural microvariability of the mAb, along with the additional heterogeneity afforded by the bioconjugation process. Top-down (TD) and middle-down (MD) strateg...
A rationally designed fluorescent probe for sulfur dioxide and its derivatives: applications in food analysis and bioimaging [0.03%]
一种用于二氧化硫及其衍生物的荧光探针及在食品分析和生物成像中的应用
Yuyu Fang,Dongbin Zheng,Tingrui Zhang et al.
Yuyu Fang et al.
Exogenous sulfur dioxide (SO2) and its derivatives (SO32-/HSO3-) have been extensively utilized in food preservation and endogenous SO2 is recognized as a significant gaseous signaling molecule that can mediate various physiological process...
Tian Tian,Shichao Lin,Chaoyong Yang
Tian Tian
Single-cell multiomics technologies empower simultaneous measurement of multiple types of molecules within individual cells, providing a more profound comprehension compared with the analysis of discrete molecular layers from different cell...
Label-free quantification of host cell protein impurity in recombinant hemoglobin materials [0.03%]
无标签定量评估重组血红蛋白材料中的宿主细胞蛋白杂质
André Henrion,Cristian-Gabriel Arsene,Maik Liebl et al.
André Henrion et al.
Quantitative analysis relies on pure-substance primary calibrators with known mass fractions of impurity. Here, label-free quantification (LFQ) is being evaluated as a readily available, reliable method for determining the mass fraction of ...
State of the art and future research directions of materials science applied to electrochemical biosensor developments [0.03%]
材料科学在电化学生物传感器研究中的最新进展及未来发展方向综述
Erich Kny,Roger Hasler,Wiktor Luczak et al.
Erich Kny et al.
Centralized laboratories in which analytical processes are automated to enable the analysis of large numbers of samples at relatively low cost are used for analytical testing throughout the world. However, healthcare is changing, partly due...
Enhancing intracellular mRNA precise imaging-guided photothermal therapy with a nucleic acid-based polydopamine nanoprobe [0.03%]
基于核酸的聚多巴胺纳米探针增强胞内mRNA精准成像引导的光热治疗
Jiayao Xu,Xiaohong Zhong,Mingzhu Fan et al.
Jiayao Xu et al.
Despite significant advancements in cancer research, real-time monitoring and effective treatment of cancer through non-invasive techniques remain a challenge. Herein, a novel polydopamine (PDA) nucleic acid nanoprobe has been developed for...
Rigorous pH measurement in non-aqueous solution: measurement method and reference values in ethanol [0.03%]
非水溶液的pH严格测定法及乙醇中的参考值
Frank Bastkowski,Agnes Heering,Emrah Uysal et al.
Frank Bastkowski et al.
The recently introduced unified pH ([Formula: see text]) concept enables rigorous pH measurements in non-aqueous and mixed media while at the same time maintaining comparability to the conventional aqueous pH scale. However, its practical a...
Recent advances in analysis of new psychoactive substances by means of liquid chromatography coupled with low-resolution tandem mass spectrometry [0.03%]
液相色谱-低分辨串联质谱分析新型精神活性物质研究进展
Bartłomiej Feigel,Piotr Adamowicz,Sławomir Wybraniec
Bartłomiej Feigel
The number of methods for the analysis of new psychoactive substances (NPS) is continually increasing, and there is no indication that this trend will change in the near future. The constantly growing market of "designer drugs" makes it nec...
Analysis and experimental assessment of an optimized SERS substrate used to detect thiabendazole in apples with high sensitivity [0.03%]
一种用于高灵敏度检测苹果中噻苯达唑的优化型SERS基底的分析与实验评估研究
Xiaodong Li,Yanyan Zhang,Muhammad Awais et al.
Xiaodong Li et al.
Pesticides that linger in the environment and ecosystems for an extended period can cause severe and dangerous health problems in humans. To detect pesticides in foods, the development of high-sensitivity and quick screening technologies wa...