Raman spectroscopy supported by machine learning reveals changes in balance of macromolecules in diabetic rat serum [0.03%]
基于机器学习的拉曼光谱揭示糖尿病大鼠血清中大分子平衡的变化
Adrianna Kryska,Joanna Depciuch,Mikolaj Krysa et al.
Adrianna Kryska et al.
In type 2 diabetes mellitus (T2DM), changes in glucose and lipid levels in serum are the first signals of disease progression. In this article, Raman spectroscopy supported with machine learning (ML) was used both to determine the level of ...
Ag NPs loading and ultraviolet irradiation strategies for enhancing the performance of WO3/Ti3C2TX composites in detecting 2-heptanone [0.03%]
Ag NPs负载和紫外线照射策略增强WO3/Ti3C2TX复合材料检测庚酮性能
Jinfu Zhang,Pei Li,Helei Yang et al.
Jinfu Zhang et al.
As a typical volatile organic compound (VOC), 2-heptanone detection is critical in food spoilage monitoring, chemical production safety control, and environmental pollutant tracking. However, developing a 2-heptanone gas sensor with high se...
Rapid and sensitive detection of polycyclic aromatic hydrocarbons using electrochemically assisted derivatization mass spectrometry [0.03%]
基于电化学衍生化质谱的多环芳烃快速灵敏检测技术
Heng-Yu Xu,Zhi-Cai Jiang,Cheng-Fei Lu et al.
Heng-Yu Xu et al.
Polycyclic aromatic hydrocarbons (PAHs) are ubiquitous toxic pollutants that pose significant risks to human health. However, because of their intrinsic non-polar properties, only moderate detection sensitivity can be achieved in the mass s...
Deciphering the formation of biogenic nanoparticles and their protein corona: State-of-the-art and analytical challenges [0.03%]
生物纳米颗粒的形成及其蛋白质冠层的研究现状与分析挑战
Andrés Suárez Priede,Miguel Gómez-Sánchez,Paula García-Cancela et al.
Andrés Suárez Priede et al.
Biogenic synthesis of nanoparticles (NPs) using biological organisms such as plants, fungi, and bacteria offers a sustainable, green alternative to conventional chemical synthesis. These green methods involve biological matrices mediating m...
Anthocyanins extraction from Amazonian matrices using natural deep eutectic solvents: characterization and ecological impact [0.03%]
基于天然深共晶溶剂的亚马逊基质花青素提取、表征及生态影响研究
Ianê Valente Pires,Antonio Manoel da Cruz Rodrigues,Carolina Turnes Pasini Deolindo et al.
Ianê Valente Pires et al.
This study investigated the effectiveness of natural deep eutectic solvents (NADES) as a green alternative to traditional organic solvents for the extraction of anthocyanins from three Amazonian matrices: açaí, mangosteen pericarp, and pu...
A novel approach to determination of amino acids and cyclic heptapeptides using imprinted proteins [0.03%]
一种新颖的利用印迹蛋白质测定氨基酸和环肽的方法
Kirill Yu Presnyakov,Polina M Ilicheva,Ivan A Reshetnik et al.
Kirill Yu Presnyakov et al.
For the first time, imprinted proteins (IPs) were used as molecular recognition elements for determination of amino acids (arginine, Arg) and heptapeptides (microcystin-LR, MC-LR) in competitive solid-phase fluorescent assay (CSPA). Bovine ...
Deciphering the binding strength of oil matrix through molecularly resolved release energy analysis using thermal slicing ramped pyrolysis GC-MS [0.03%]
基于热切分子解析裂解气相色谱-质谱的原油组分结合强度分析方法研究
Kaijun Lu,Jianhong Xue,Zhanfei Liu
Kaijun Lu
Recent advancements in analytical techniques have significantly furthered our understanding of the chemical composition of petroleum and its derivatives. However, there remains a missing link connecting the molecular structure with how spec...
How does NMR support SARS-CoV-2 protein-ligand interaction studies? [0.03%]
NMR技术如何助力新冠病毒蛋白质小分子相互作用研究？
Norazlan Mohmad Misnan,Azira Muhamad,Mohd Ridzuan Mohd Abd Razak et al.
Norazlan Mohmad Misnan et al.
The COVID-19 pandemic has highlighted the urgent need for effective antiviral strategies against SARS-CoV-2. Nuclear magnetic resonance (NMR) spectroscopy has played a critical role by providing detailed insights into protein-ligand interac...
An integrated pH "Pen" for visual nucleic acid detection based on colorimetrical LAMP at point-of-care testing [0.03%]
一种基于比色LAMP的即时可视化核酸检测集成pH“笔”
Lei Wang,Zhifeng Wu,Jing Niu et al.
Lei Wang et al.
Nucleic acid detection serves as a critical tool employed for controlling the spread of infectious diseases. However, the majority of current nucleic acid detection methods still rely on large and complex equipment, rendering them unsuitabl...
Method validation and analysis of halogenated natural products (HNPs) in seafood samples [0.03%]
卤代天然产物（HNPs）的检测方法验证及海水样本中HNPs的分析研究
Marco Krämer,Walter Vetter,Oliver Kappenstein et al.
Marco Krämer et al.
Halogenated natural products (HNPs) are a diverse group of organohalogen compounds, predominantly found in the marine environment. Selected HNPs show structural similarity to persistent organic pollutants (POPs), but data on their occurrenc...