Differences in the Performance of Allyl Based Palladium Precatalysts for Suzuki-Miyaura Reactions [0.03%]
用于 Suzuki-Miyaura 反应的烯丙基钯预催化剂性能差异研究
Matthew R Espinosa,Angelino Doppiu,Nilay Hazari
Matthew R Espinosa
Palladium(II) precatalysts are used extensively to facilitate cross-coupling reactions because they are bench stable and give high activity. As a result, precatalysts such as Buchwald's palladacycles, Organ's PEPPSI species, Nolan's allyl-b...
Jacob Werth,Kristen Berger,Christopher Uyeda
Jacob Werth
Cobalt pyridine-diimine (PDI) complexes catalyze the reductive spirocyclopropanation of terminal 1,3-dienes. gem-Dichlorocycloalkanes serve as carbene precursors and Zn is used as a terminal electron source. The reaction is effective for a ...
Asymmetric Nazarov Cyclizations of Unactivated Dienones by Hydrogen-Bond-Donor/Lewis Acid Co-Catalyzed, Enantioselective Proton-Transfer [0.03%]
氢键供体/路易斯酸共催化非活化二烯酮的对映选择性质子转移及不对称纳扎罗夫环化反应
Jan B Metternich,Martin Reiterer,Eric N Jacobsen
Jan B Metternich
We report an enantioselective Nazarov cyclization catalyzed by chiral hydrogen-bond-donors in concert with silyl Lewis acids. The developed transformation provides access to tri-substituted cyclopentenones in high levels of enantioselectivi...
Catalytic Reductions Without External Hydrogen Gas: Broad Scope Hydrogenations with Tetrahydroxydiboron and a Tertiary Amine [0.03%]
无需外部氢气的催化还原反应：四羟基二硼和叔胺作用下的广谱氢化反应
Kirill A Korvinson,Hari K Akula,Casina T Malinchak et al.
Kirill A Korvinson et al.
Facile reduction of aryl halides with a combination of 5% Pd/C, B2(OH)4, and 4-methylmorpholine is reported. Aryl bromides, iodides, and chlorides were efficiently reduced. Aryl dihalides containing two different halogen atoms underwent sel...
Hydroalkylation of Aryl Alkenes with Organohalides Catalyzed by Molybdenum Oxido Based Lewis Pairs [0.03%]
基于钼氧路易斯对催化芳基烯烃与有机卤化物的羟烷基化反应
Niklas Zwettler,Antoine Dupé,Sumea Klokić et al.
Niklas Zwettler et al.
Three molybdenum(VI) dioxido complexes [MoO2(L)2] bearing Schiff base ligands were reacted with B(C6F5)3 to afford the corresponding adducts [MoO{OB(C6F5)3}(L)2], which were fully characterized. They exhibit Frustrated Lewis-Pairs reactivit...
Marvin Kischkewitz,Florian W Friese,Armido Studer
Marvin Kischkewitz
1,2-Boron ate rearrangements represent a fundamental class of transformations to establish new C-C bonds while retaining the valuable boron moiety in the product. In established ionic processes, the boron ate complex is activated by an exte...
Pyridine(diimine) Iron Diene Complexes Relevant to Catalytic [2+2]-Cycloaddition Reactions [0.03%]
与催化[2+2]环加成反应相关的吡啶二亚胺铁二烯配合物
C Rose Kennedy,Hongyu Zhong,Matthew V Joannou et al.
C Rose Kennedy et al.
The synthesis, characterization, and catalytic activity of pyridine(diimine) iron piperylene and isoprene complexes are described. These diene complexes are competent precatalysts for (i) the selective cross-[2+2]-cycloaddition of butadiene...
Continuous Flow Bioamination of Ketones in Organic Solvents at Controlled Water Activity using Immobilized ω-Transaminases [0.03%]
利用固定化ω-转氨酶以可控水活度在有机溶剂中连续流动生物胺化酮类化合物
Wesley Böhmer,Alexey Volkov,Karim Engelmark Cassimjee et al.
Wesley Böhmer et al.
Compared with biocatalysis in aqueous media, the use of enzymes in neat organic solvents enables increased solubility of hydrophobic substrates and can lead to more favorable thermodynamic equilibria, avoidance of possible hydrolytic side r...
Technology Trends of Catalysts in Hydrogenation Reactions: A Patent Landscape Analysis [0.03%]
氢化反应催化剂技术发展趋势：基于专利文献的分析研究
Marius A Stoffels,Felix J R Klauck,Thomas Hamadi et al.
Marius A Stoffels et al.
The purpose of this review is to present an overview of the patent landscape for catalysts used in hydrogenation reactions. Based on patent data extracted from PatBase®, we use predefined patent classifications as well as a keyword-based s...
B(C6F5)3-Catalyzed α-Deuteration of Bioactive Carbonyl Compounds with D2O [0.03%]
B(C6F5)3催化生物活性羰基化合物的D2Oα-氘代反应
Yejin Chang,Tanner Myers,Masayuki Wasa
Yejin Chang
An efficient deuteration process of α-C-H bonds in various carbonyl-based pharmaceutical compounds has been developed. Catalytic reactions are initiated by the action of Lewis acidic B(C6F5)3 and D2O, converting a drug molecule into the co...