首页 正文

B(C6F5)3-Catalyzed α-Deuteration of Bioactive Carbonyl Compounds with D2O

{{output}}
An efficient deuteration process of α-C-H bonds in various carbonyl-based pharmaceutical compounds has been developed. Catalytic reactions are initiated by the action of Lewis acidic B(C6F5)3 and D2O, converting a drug molecule into the corresponding boron-en... ...