Melatonin Promotes the Synthesis and Secretion of Growth Hormone in the Adenohypophysis by Activating the cAMP/FOXO1 Pathway [0.03%]
Yi Zheng,Qing-Qing Chen,Hai-Xiang Guo et al.
Yi Zheng et al.
Melatonin, a signaling molecule secreted by the pineal gland, is closely associated with physiological activities, such as animal growth, development, and reproduction. Multiple studies have indicated that melatonin acts on the adenohypophy...
Early-Life Melatonin Supplementation Reduces the Long-Term Behavioral, Morphological, and Molecular Alterations in a Rat Model of Autism Spectrum Disorder [0.03%]
Luis J Hernández-Sierra,Roberto C Salgado-Delgado,Osvaldo Ibáñez-Sandoval et al.
Luis J Hernández-Sierra et al.
Autism spectrum disorder (ASD) is a complex neurodevelopmental condition characterized by significant challenges in social interactions and repetitive behaviors. Its prevalence is high, with males affected at a rate four times higher than f...
Melatonin Enhances the Myometrial Contraction Through MT2-PKC-NRF2/MAFF Signaling Pathway in Sows [0.03%]
Tongjuan Niu,Yewen Zhou,Guobin Qiu et al.
Tongjuan Niu et al.
Spontaneous parturition in both humans and sows occurs predominantly at night. Melatonin is thought to facilitate nocturnal parturition in humans by synergistically enhancing myometrial contractions with oxytocin, but the precise underlying...
Brain-Targeted RVG-Liposomal Melatonin Ameliorates Manganese Neurotoxicity by Enhancing Neurogenesis and Modulating Systemic Amino Acid Profiles [0.03%]
Xueting Wang,Junge Chen,Jiao Xia et al.
Xueting Wang et al.
Chronic manganese (Mn) exposure induces severe neurotoxicity, characterized by impaired neurogenesis and disrupted metabolic homeostasis. Although melatonin (MT) possesses established neuroprotective properties, its clinical utility is hind...
Low-Dose Melatonin, Climacteric Symptoms and Sleep in Female Shift Workers: A Randomized Controlled Trial [0.03%]
Susy P Saraiva,Carolina V R D&#x;Aurea,Cristina S S Luz et al.
Susy P Saraiva et al.
Sleep disturbances and mood changes are common during the climacteric, often linked to hormonal fluctuations caused by reduced ovarian function. Evidence suggests that long-term melatonin administration may improve the quality of life in cl...
Randomized Controlled Trial
Journal of pineal research. 2026 Mar;78(2):e70140. DOI:10.1111/jpi.70140 2026
Can Morning Light Phase Advance Human Melatonin Rhythms in Less Than 24 h? [0.03%]
清晨的光线能否使人体内的褪黑激素节奏提前少于24小时？
Clara López-Velasco,Carolin Franziska Reichert,Christian Cajochen
Clara López-Velasco
Light is the primary cue that synchronises the human circadian system to the 24-h day, advancing or delaying circadian rhythms depending on its timing. While it is known that morning light induces phase advances, most studies assess the tim...
Melatonin Protects Mouse Oocytes From the Environmental Toxicant 6PPD-Quinone by Preserving Mitochondrial and Endomembrane Homeostasis [0.03%]
褪黑素通过维持线粒体和内膜系统稳态来保护小鼠卵母细胞免受环境毒素6PPD-quinone的伤害
Bei Chen,Jiaqi Wang,Qianrong Qi et al.
Bei Chen et al.
N-(1,3-dimethylbutyl)-N'-phenyl-p-phenylenediamine-quinone (6PPD-Q) is a ubiquitous tire-derived transformation product with emerging reproductive toxicity; however, its impact on mammalian oocytes and the potential protective role of melat...
RETRACTION: Induction of Matrix Metalloproteinase-9 and -3 in Nonsteroidal Anti-Inflammatory Drug-Induced Acute Gastric Ulcers in Mice: Regulation by Melatonin [0.03%]
撤稿：非甾体抗炎药诱导的小鼠急性胃溃疡中明托敏对基质金属蛋白酶-9和-3的调节作用
K. Ganguly and S. Swarnakar, "Induction of Matrix Metalloproteinase-9 and -3 in Nonsteroidal Anti-Inflammatory Drug-Induced Acute Gastric Ulcers in Mice: Regulation by Melatonin," Journal of Pineal Research 47, no. 1 (2009): 43-55, https://...
Melatonin Is Bound to a Glycolytic Protein Complex via Tdh2p During Fermentation in Saccharomyces cerevisiae [0.03%]
丝状酿酒酵母中褪黑素通过Tdh2p与糖酵解蛋白复合物结合
Sandra Martín-Esteban,Joseph J Rossi,Cristobal A Onetto et al.
Sandra Martín-Esteban et al.
Melatonin (MEL) is a multifunctional bioactive compound known for its antioxidant properties and regulatory roles in both animal and microbial systems. Although MEL has been shown to interact with glycolytic enzymes in yeast, the molecular ...