The Pineal Gland Is Required for Optimal Nighttime Immunity to Bacterial Infection in Larval Zebrafish [0.03%]
视交叉上核对斑马鱼幼鱼细菌感染的夜间免疫至关重要
Gabriel Anasarias-Dumo,Yevetta Y Xiang,David Cumin et al.
Gabriel Anasarias-Dumo et al.
The immune response to bacterial infection demonstrates circadian rhythmicity, with heightened antibacterial immunity often observed during the daytime. This circadian-gated immune response is believed to have evolved to synchronize peak an...
Impact of Human Melanopsin Gene (OPN4) Polymorphisms (I394T, P10L) on Nocturnal Melatonin and Daily Rhythms in Young Adults [0.03%]
人类黑素皮质素基因(OPN4)多态性(I394T，P10L)对年轻成人夜间褪黑素和日常节律的影响
Jesús Vicente-Martínez,María Ángeles Bonmatí-Carrión,Ana María López-Parra et al.
Jesús Vicente-Martínez et al.
The present study investigates the impact of two missense SNPs in the human melanopsin gene OPN4 -I394T (rs1079610) and P10L (rs2675703)- on non-image-forming (NIF) physiological and behavioural outputs in healthy young adults under real-wo...
Impact of Human Melanopsin Gene (OPN4) Polymorphisms (I394T, P10L) on Nocturnal Melatonin and Daily Rhythms in Young Adults [0.03%]
人视黑素蛋白基因(OPN4)多态性(I394T，P10L)对年轻成人夜间褪黑素和昼夜节律的影响
Jesús Vicente-Martínez,María Ángeles Bonmatí-Carrión,Ana María López-Parra et al.
Jesús Vicente-Martínez et al.
The present study investigates the impact of two missense SNPs in the human melanopsin gene OPN4 -I394T (rs1079610) and P10L (rs2675703)- on non-image-forming (NIF) physiological and behavioural outputs in healthy young adults under real-wo...
Melatonin Suppresses Osteoclastogenesis via Inhibiting Iron/ROS-CREB/PGC-1β-Mediated Mitochondrial Biogenesis [0.03%]
褪黑素通过抑制铁/ROS-CREB/PGC-1β介导的线粒体生物生成来抑制破骨细胞生成
Jiancheng Yang,Jingmin Che,Ming Yang et al.
Jiancheng Yang et al.
Postmenopausal osteoporosis (PMOP) is linked to iron accumulation. Melatonin has iron-chelating and antioxidant properties, but its mechanism against osteoclastogenesis remains unclear. This study investigated whether melatonin suppresses o...
Melatonin Seed Coating Improves Soybean Growth in Association With Rhizosphere Physiological and Bacterial Community Shifts: Melatonin Alters Soybean Rhizosphere Responses [0.03%]
褪黑素包衣通过改变大豆根系土壤生理和细菌群落提高大豆生长：褪黑素改变了大豆根系的响应
Liang Cao,Weiran Ma,Hui Wen et al.
Liang Cao et al.
Melatonin (MT), a potent bioactive molecule, regulates plant development and stress resistance. However, in complex field environments, how MT seed coating recruits soil microbes via root development modulation and exudate release to boost ...
The Melatonin-Nitric Oxide Signaling Pathway Alleviates Iron Starvation by Mobilizing Apoplastic Iron Pools and Reshaping Iron Transport in Rice (Oryza sativa L.) [0.03%]
褪黑素-一氧化氮信号途径通过动员水稻(oryza sativa l.)胞外铁库和重塑其铁转运来缓解缺铁压力
Jing Huang,Hao Yu Wang,Zheng Tong Jing et al.
Jing Huang et al.
Iron (Fe) is indispensable for plant growth and development. Notably, melatonin (MT) serves as a key regulator to improve plant tolerance under nutrient stress conditions. Currently, the exact mechanism regulating MT's involvement in the ri...
Exogenous Melatonin Compensates for Moderate Nitrogen Reduction in Upland Rice by Optimizing Leaf Nitrogen Allocation and Photosynthetic Metabolism [0.03%]
外源褪黑素通过优化叶片氮素分配和光合代谢补偿水稻减氮的产量损失
Qin Bin,Ji Leyao,Jiang Meixuan et al.
Qin Bin et al.
Moderate nitrogen (N) reduction can lower production costs in upland rice but may constrain photosynthesis, N assimilation, and yield formation. Melatonin has the potential to regulate photosynthesis and nutrient metabolism; however, whethe...
Promoter-Level Regulation of Melatonin Biosynthesis in Plant Stress Responses: A Framework for Climate-Resilient Crop Improvement [0.03%]
植物应对逆境反应中褪黑素生物合成的启动子水平调节：气候复原力作物改良的框架
Muhammad Hafeez Ullah Khan,Ali Muhammad,Lijie Li et al.
Muhammad Hafeez Ullah Khan et al.
Climate change increasingly exposes crops to overlapping abiotic and biotic stresses, creating a need for regulatory strategies that improve stress tolerance without imposing unnecessary fitness costs under favorable conditions. Melatonin h...
Specific Knockdown of Gene Expression in the Mature Rat Pineal Gland: The Cone-Rod Homeodomain Transcription Factor Regulates Melatonin Synthesis In Vivo [0.03%]
成熟大鼠松果体特异性基因沉默：视锥/视杆家园盒转录因子通过调节芳基硫酸酯酶活性影响体内松果体生成的生理节律
Nicole Anne Morrissey,Tenna Bering,Aurea Susana Blancas-Velázquez et al.
Nicole Anne Morrissey et al.
Melatonin is synthesised from tryptophan by the sequential action of enzymes that are highly expressed in the pineal gland. Homeobox gene-encoded transcription factors typically control organ development; however, a set of homeobox genes is...
EXPRESSION OF CONCERN: Melatonin Prevents Cadmium-Induced Bone Damage: First Evidence on an Improved Osteogenic/Adipogenic Differentiation Balance of Mesenchymal Stem Cells as Underlying Mechanism [0.03%]
撤稿声明：褪黑素可预防镉致骨损伤：首次证据表明，间充质干细胞成骨/成脂分化平衡的改善可能是其潜在机制
L. Knani, D. Bartolini, S. Kechiche, C. Tortoioli, G. Murdolo, M. Moretti, I. Messaoudi, R. J. Reiter, and F. Galli, "Melatonin Prevents Cadmium-Induced Bone Damage: First Evidence on an Improved Osteogenic/Adipogenic Differentiation Balanc...