Physiological, Biochemical, and Omics Mechanisms Underlying Melatonin-Mediated Salinity Tolerance and Yield Stability in Adzuki Bean [0.03%]
盐胁迫下赤豆生理生化及组学层面对抗机制研究——褪黑素介导的耐盐性和稳产性响应
Liang Cao,Xinyu Guan,Hui Wen et al.
Liang Cao et al.
Salinity stress is a critical abiotic factor limiting the growth and yield of legume crops by inhibiting photosynthesis, exacerbating oxidative damage, and disrupting the balance of carbon (C) and nitrogen (N) metabolism. This study aimed t...
Melatonin Facts: Musing With the Concept "Melatonin Travels Freely Through Biological Membranes" [0.03%]
褪黑素事实：思考“褪黑素自由通过生物膜”这一概念
Jean A Boutin,Jérôme Leprince,Ralf Jockers
Jean A Boutin
Melatonin has been shown to travel freely through biological membranes. The consequences of this demonstration have been largely underestimated these past years. In particular, the behavior of melatonin during the preparation of samples fro...
Melatonin Receptor-Mediated Signaling and PGPR-Induced Secondary Metabolic Defense Dome Confer Cadmium Tolerance in Brassica juncea: Transcriptomic and Docking Insights [0.03%]
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Tamanna Bhardwaj,Renu Bhardwaj,Nancy Sharma et al.
Tamanna Bhardwaj et al.
Anthropogenic activities have increased cadmium (Cd) accumulation in agricultural soils, severely affecting crop productivity. This study investigated the role of melatonin (Mlt) and a Pseudomonas consortium (PGPR) in modulating secondary m...
Melatonin Promotes the Synthesis and Secretion of Growth Hormone in the Adenohypophysis by Activating the cAMP/FOXO1 Pathway [0.03%]
褪黑素通过激活cAMP/FOXO1信号通路促进腺垂体生长激素的合成与分泌
Yi Zheng,Qing-Qing Chen,Hai-Xiang Guo et al.
Yi Zheng et al.
Melatonin, a signaling molecule secreted by the pineal gland, is closely associated with physiological activities, such as animal growth, development, and reproduction. Multiple studies have indicated that melatonin acts on the adenohypophy...
Early-Life Melatonin Supplementation Reduces the Long-Term Behavioral, Morphological, and Molecular Alterations in a Rat Model of Autism Spectrum Disorder [0.03%]
生命早期褪黑素补充减轻自闭症谱系障碍大鼠模型的长期行为、形态和分子改变
Luis J Hernández-Sierra,Roberto C Salgado-Delgado,Osvaldo Ibáñez-Sandoval et al.
Luis J Hernández-Sierra et al.
Autism spectrum disorder (ASD) is a complex neurodevelopmental condition characterized by significant challenges in social interactions and repetitive behaviors. Its prevalence is high, with males affected at a rate four times higher than f...
Melatonin Enhances the Myometrial Contraction Through MT2-PKC-NRF2/MAFF Signaling Pathway in Sows [0.03%]
褪黑素通过MT2-PKC-NRF2/MAFF信号途径增强母猪子宫收缩功能研究
Tongjuan Niu,Yewen Zhou,Guobin Qiu et al.
Tongjuan Niu et al.
Spontaneous parturition in both humans and sows occurs predominantly at night. Melatonin is thought to facilitate nocturnal parturition in humans by synergistically enhancing myometrial contractions with oxytocin, but the precise underlying...
Brain-Targeted RVG-Liposomal Melatonin Ameliorates Manganese Neurotoxicity by Enhancing Neurogenesis and Modulating Systemic Amino Acid Profiles [0.03%]
脑靶向RVG-脂质体褪黑素通过促进神经发生和调节全身氨基酸谱来改善锰神经毒性
Xueting Wang,Junge Chen,Jiao Xia et al.
Xueting Wang et al.
Chronic manganese (Mn) exposure induces severe neurotoxicity, characterized by impaired neurogenesis and disrupted metabolic homeostasis. Although melatonin (MT) possesses established neuroprotective properties, its clinical utility is hind...
Low-Dose Melatonin, Climacteric Symptoms and Sleep in Female Shift Workers: A Randomized Controlled Trial [0.03%]
小剂量褪黑素、女性倒班工人绝经症状和睡眠的一项随机对照试验
Susy P Saraiva,Carolina V R D&#x;Aurea,Cristina S S Luz et al.
Susy P Saraiva et al.
Sleep disturbances and mood changes are common during the climacteric, often linked to hormonal fluctuations caused by reduced ovarian function. Evidence suggests that long-term melatonin administration may improve the quality of life in cl...
Randomized Controlled Trial
Journal of pineal research. 2026 Mar;78(2):e70140. DOI:10.1111/jpi.70140 2026
Can Morning Light Phase Advance Human Melatonin Rhythms in Less Than 24 h? [0.03%]
清晨的光线能否使人体内的褪黑激素节奏提前少于24小时？
Clara López-Velasco,Carolin Franziska Reichert,Christian Cajochen
Clara López-Velasco
Light is the primary cue that synchronises the human circadian system to the 24-h day, advancing or delaying circadian rhythms depending on its timing. While it is known that morning light induces phase advances, most studies assess the tim...
Melatonin Protects Mouse Oocytes From the Environmental Toxicant 6PPD-Quinone by Preserving Mitochondrial and Endomembrane Homeostasis [0.03%]
褪黑素通过维持线粒体和内膜系统稳态来保护小鼠卵母细胞免受环境毒素6PPD-quinone的伤害
Bei Chen,Jiaqi Wang,Qianrong Qi et al.
Bei Chen et al.
N-(1,3-dimethylbutyl)-N'-phenyl-p-phenylenediamine-quinone (6PPD-Q) is a ubiquitous tire-derived transformation product with emerging reproductive toxicity; however, its impact on mammalian oocytes and the potential protective role of melat...