Specific Knockdown of Gene Expression in the Mature Rat Pineal Gland: The Cone-Rod Homeodomain Transcription Factor Regulates Melatonin Synthesis In Vivo
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Melatonin is synthesised from tryptophan by the sequential action of enzymes that are highly expressed in the pineal gland. Homeobox gene-encoded transcription factors typically control organ development; however, a set of homeobox genes is strongly expressed ... ...