Correction to: Innovating non‑small cell lung cancer treatment with novel TM‑GL/NPs nanoparticles for Glycitin delivery [0.03%]
非小细胞肺癌新型TM-GL/NPs纳米颗粒递送甘цит汀创新治疗的更正通知
Chang Liu,Jiabao Zhao,Jun Liu et al.
Chang Liu et al.
Published Erratum
Cell biology and toxicology. 2025 Oct 10;41(1):138. DOI:10.1007/s10565-025-10108-5 2025
Characterization of SPTLC2 as a key driver promoting microglial activation and energy metabolism reprogramming after ischemic stroke through bulk and single-cell analyses combined with experimental validation [0.03%]
联合群体和单细胞分析及实验验证表征SPTLC2作为缺血性卒中后促进小胶质细胞活化和能量代谢重编程的关键驱动因素
Yongxing Lai,Peiqiang Lin,Zhiyun Wu et al.
Yongxing Lai et al.
Background: Ischemic stroke (IS) stands as a principal contributor to high rates of sickness and death. The condition's pathological development is complicated, featuring mechanisms like mitochondrial impairment and the a...
Targeting Skp2 by Tanshinone IIA overcomes chemoresistance in colorectal cancer [0.03%]
丹参酮IIA通过作用于Skp2克服结直肠癌的化疗耐药性
Xin Dong,Kexin Li,Ruirui Wang et al.
Xin Dong et al.
Fluorouracil (5-Fu)-based chemotherapy is a first-line treatment option for advanced colorectal cancer (CRC). However, long-term use of 5-Fu often leads to chemoresistance, which limits its therapeutic efficacy, highlighting the need for de...
Wei Chen,Zeze Zhao,Zhengguang Geng et al.
Wei Chen et al.
Sepsis-induced cardiomyopathy (SICM), a critical contributor to the high mortality rate associated with sepsis, involves complex pathophysiological mechanisms that remain incompletely elucidated. In recent years, dysregulation of bidirectio...
Increased reactive astrocytes in hippocampal CA1 region mediated by decreased CXCR7 is involved in postoperative cognitive dysfunction in aged mice [0.03%]
CXCR7表达下调诱导的反应性星形胶质细胞活化参与老年小鼠术后认知功能障碍病理发生发展
Qiang Liu,Chen-Rui Zhou,Hai-Bi Wang et al.
Qiang Liu et al.
Postoperative cognitive dysfunction (POCD) is a prevalent neurological complication that significantly impairs recovery in elderly surgical patients. While astrocyte activation has been implicated in various neurodegenerative disorders, its...
scRNA-seq deciphers molecular mechanisms of endocrine disruptor 4-nonylphenol impairing spermatogenesis in mice [0.03%]
单细胞 RNA 测序解码环境内分泌干扰物 4-壬基酚损害小鼠生精的分子机制
Xue Zhao,Yanan Tian,Dan Zhou et al.
Xue Zhao et al.
4-Nonylphenol (NP) is an environmental endocrine disruptor widely used in consumer products. Previous studies have shown that NP can interfere with hormone synthesis and metabolism in humans and animals, leading to male reproductive dysfunc...
METTL3-driven m⁶A epigenetics in gastric cancer: unveiling oncogenic networks and clinical translation from tumorigenesis to therapy resistance [0.03%]
胃癌中的METTL3介导的m⁶A表观遗传重编程：从肿瘤发生到耐药的致癌网络及临床转化研究
Xiaohong Fu,Xia Ruan,Jie He
Xiaohong Fu
Globally, gastric cancer (GC) ranks among the deadliest malignancies due to frequent late-stage detection, metastatic dissemination, and resistance to therapies. Emerging evidence highlights N⁶-methyladenosine (m⁶A) modification, orchestr...
Repeated exposure to CoCr28Mo6 particles leads to activation of NLRP3 inflammasome signaling in human osteoblasts [0.03%]
反复暴露于CoCr28Mo6颗粒可激活人成骨细胞的NLRP3炎性体信号通路
Marie-Luise Sellin,Luca Marit Koentopp,Rainer Bader et al.
Marie-Luise Sellin et al.
Interleukin (IL)-1β and IL-18 are involved in the inflammatory response of wear-induced osteolysis. The production and secretion of these interleukins are regulated by the nucleotide-binding oligomerization domain leucine-rich repeat-conta...
SP1 and p23 play a crucial role in the circadian target gene induction of activated aryl hydrocarbon receptor in human breast cells [0.03%]
SP1和p23在活化的芳香烃受体诱导人乳腺细胞circadian目标基因表达中起关键作用
Melina Mihelakis,Tanina Flore,Gilbert Schönfelder et al.
Melina Mihelakis et al.
The Aryl Hydrocarbon Receptor (AHR) is a crucial mediator of cellular responses upon exposure to environmental pollutants. Initially described as central activator in xenobiotic metabolism, recent research has unveiled additional layers of ...
Celastrol modulates IRS1 expression to alleviate ovarian aging and to enhance follicular development [0.03%]
Celastrol通过调节IRS1表达缓解卵巢衰老和促进卵泡发育
Yao Jiang,Yonghua Shi,Meng Lv et al.
Yao Jiang et al.
Ovarian aging significantly contributes to the decline of the female reproductive system, adversely affecting fertility and endocrine homeostasis. To address the challenges posed by reproductive aging, natural products have shown promising ...