Molecular characteristics of apolipoprotein M and its biological functions in kidney diseases [0.03%]
肾病相关脂蛋白代谢及新型抗纤维化药物研发探索
Jingjin Tao,Yuan Tan,Shuo Yang et al.
Jingjin Tao et al.
Apolipoprotein M (apoM) is a subclass of apolipoproteins primarily found in high-density lipoprotein (HDL), it was mainly expressed and secreted in the liver and kidneys. ApoM functions as the carrier of sphingosine-1-phosphate (S1P) to for...
Ferroptosis in prostatitis: pathogenic mechanisms and therapeutic advances [0.03%]
前列腺炎中的铁死亡:发病机制与治疗进展
Jintao Shi,Qinyu Zhang,Yang Xuan et al.
Jintao Shi et al.
Cancer-associated fibroblasts-secreted exosomes promote malignant advancement of liver cancer by regulating the circE2F3/miR-1305/E2F3 axis [0.03%]
癌相关成纤维细胞分泌的外泌体通过调节circE2F3 / miR-1305 / E2F3轴促进肝癌恶性进展
Wei Dong,Yutong Liu,Pu Yan et al.
Wei Dong et al.
Loop of N2-polarized neutrophils and exhausted CD8 + T cells induces immunotherapy resistance in NSCLC [0.03%]
N2极化中性粒细胞和耗竭的CD8+T细胞诱导非小细胞肺癌免疫治疗耐药性
Zhansheng Zou,Zhiyu Guo,Yuanhao Wei et al.
Zhansheng Zou et al.
While neutrophils represent a prominent myeloid component in non-small cell lung cancer (NSCLC), the specific immunosuppressive functions of N2-polarized neutrophils and their mechanistic interactions with CD8⁺ T cells remain incompletely ...
RNase A is inhibited by the cysteine-rich protein thionein but not by the metal-containing form metallothionein [0.03%]
巯基蛋白而不是金属硫蛋白可抑制核糖核酸酶A的作用
Francisco Trujillo-González,Ian Asaf Muñoz-Granados,Brenda L Sanchez-Gaytan et al.
Francisco Trujillo-González et al.
Decoding dexmedetomidine's multiple mechanisms in atherosclerosis: effects on lipid metabolism, inflammation, cholesterol efflux, and foam cell formation [0.03%]
度米芬多在动脉粥样硬化中的多重机制解析:对脂质代谢、炎症、胆固醇流出和泡沫细胞形成的影响
Minli Zhang,Lingling Yang,Dan Zhao
Minli Zhang
Targeting pH regulation in cancer: combined mild alkaline treatment and NHE1 inhibition as a potential therapy for clear cell renal cell carcinoma [0.03%]
针对癌症的pH调节:轻度碱处理与NHE1抑制联合治疗透明细胞肾癌的潜在疗法
Ana Beatriz Celi,Ana Mechali,Natalia Beltramone et al.
Ana Beatriz Celi et al.
RNF125 promotes CD8 T cell-mediated anticancer immunity and suppresses the malignant phenotype of cervical cancer [0.03%]
RNF125促进CD8T细胞介导的抗癌免疫并抑制宫颈癌恶性表型
Di Yang,Jia Liu,Yan Gao et al.
Di Yang et al.
Cervical cancer (CC) is a prevalent malignancy in women; however, the efficacy of immunotherapy in this disease is suboptimal, highlighting the need for novel therapeutic targets. We found that low RNF125 expression correlated with poor pro...
Unraveling the role of cuproptosis in pulmonary fibrosis pathogenesis and prognosis: an integrative single-cell transcriptomics and microarray analysis [0.03%]
杯riz蛋白诱导的细胞死亡在肺纤维化发生和发展中的作用及预后标志物研究:单细胞转录组和基因芯片数据分析
Mengting Chen,Jialu Chen,Jiaxiang Zhang et al.
Mengting Chen et al.
Pulmonary fibrosis (PF), a progressive interstitial lung disease with elusive pathogenesis, remains a therapeutic challenge. Emerging evidence suggests cuproptosis-a copper-dependent cell death pathway-may play a regulatory role in disease ...
Retraction Note: ALKBH5 inhibits thyroid cancer progression by promoting ferroptosis through TIAM1-Nrf2/HO-1 axis [0.03%]
撤回 notice:ALKBH5通过TIAM1-Nrf2/HO-1轴促进铁死亡来抑制甲状腺癌进展
Wei Li,Guo Huang,Jinrong Wei et al.
Wei Li et al.