Cancer-associated fibroblasts-secreted exosomes promote malignant advancement of liver cancer by regulating the circE2F3/miR-1305/E2F3 axis [0.03%]
Wei Dong,Yutong Liu,Pu Yan et al.
Wei Dong et al.
Loop of N2-polarized neutrophils and exhausted CD8 + T cells induces immunotherapy resistance in NSCLC [0.03%]
Zhansheng Zou,Zhiyu Guo,Yuanhao Wei et al.
Zhansheng Zou et al.
While neutrophils represent a prominent myeloid component in non-small cell lung cancer (NSCLC), the specific immunosuppressive functions of N2-polarized neutrophils and their mechanistic interactions with CD8⁺ T cells remain incompletely ...
RNase A is inhibited by the cysteine-rich protein thionein but not by the metal-containing form metallothionein [0.03%]
Francisco Trujillo-González,Ian Asaf Muñoz-Granados,Brenda L Sanchez-Gaytan et al.
Francisco Trujillo-González et al.
Decoding dexmedetomidine's multiple mechanisms in atherosclerosis: effects on lipid metabolism, inflammation, cholesterol efflux, and foam cell formation [0.03%]
Minli Zhang,Lingling Yang,Dan Zhao
Minli Zhang
Targeting pH regulation in cancer: combined mild alkaline treatment and NHE1 inhibition as a potential therapy for clear cell renal cell carcinoma [0.03%]
Ana Beatriz Celi,Ana Mechali,Natalia Beltramone et al.
Ana Beatriz Celi et al.
RNF125 promotes CD8 T cell-mediated anticancer immunity and suppresses the malignant phenotype of cervical cancer [0.03%]
Di Yang,Jia Liu,Yan Gao et al.
Di Yang et al.
Cervical cancer (CC) is a prevalent malignancy in women; however, the efficacy of immunotherapy in this disease is suboptimal, highlighting the need for novel therapeutic targets. We found that low RNF125 expression correlated with poor pro...
Unraveling the role of cuproptosis in pulmonary fibrosis pathogenesis and prognosis: an integrative single-cell transcriptomics and microarray analysis [0.03%]
Mengting Chen,Jialu Chen,Jiaxiang Zhang et al.
Mengting Chen et al.
Pulmonary fibrosis (PF), a progressive interstitial lung disease with elusive pathogenesis, remains a therapeutic challenge. Emerging evidence suggests cuproptosis-a copper-dependent cell death pathway-may play a regulatory role in disease ...
Retraction Note: ALKBH5 inhibits thyroid cancer progression by promoting ferroptosis through TIAM1-Nrf2/HO-1 axis [0.03%]
撤回 notice:ALKBH5通过TIAM1-Nrf2/HO-1轴促进铁死亡来抑制甲状腺癌进展
Wei Li,Guo Huang,Jinrong Wei et al.
Wei Li et al.
Advances in signaling pathway networks involving LHPP in various diseases [0.03%]
LHPP在各种疾病中的信号通路网络研究进展
Xuan Cai,Yalin Zhang,Lu Zhao et al.
Xuan Cai et al.
Phospholysine phosphohistidine inorganic pyrophosphate phosphatase (LHPP) is a newly discovered histidine phosphatase that can remove histidine-linked phosphate groups from proteins, but its function is unclear. Given that the LHPP protein ...
Targeting EIF5A suppresses liver fibrosis through impairment of mitochondrial function in hepatic stellate cells [0.03%]
靶向EIF5A通过损害肝星状细胞的线粒体功能抑制肝纤维化
Yuzhu Di,Lubo Jin,Xiaoyu Zhang et al.
Yuzhu Di et al.
Liver fibrosis represents a significant clinical challenge. While targeting activated hepatic stellate cells (HSCs) is a promising therapeutic strategy, the specific role of Eukaryotic Translation Initiation Factor 5 A (EIF5A) in this proce...