LncRNA HCP5 Participates in the Tregs Functions in Allergic Rhinitis and Drives Airway Mucosal Inflammatory Response in the Nasal Epithelial Cells [0.03%]
长链非编码RNA HCP5参与过敏性鼻炎Tregs功能并驱动鼻黏膜上皮细胞炎症反应
Chen Yang,Chengfang Shangguan,Changing Cai et al.
Chen Yang et al.
Allergic rhinitis (AR) is an allergic disease characterized as (immunoglobulin, IgE)-mediated type I hypersensitivity disorder. Regulatory T cells (Tregs) play a crucial role in AR. In the present study, we aimed to investigate the mechanis...
Dynamic Changes of NCR- Type 3 Innate Lymphoid Cells and Their Role in Mice with Bronchopulmonary Dysplasia [0.03%]
NCR型固有淋巴细胞在支气管肺发育不良小鼠中的动态变化及作用机制研究
Jiayu Cai,Hongyan Lu,Zhaoliang Su et al.
Jiayu Cai et al.
Inflammation is one of the important pathogenesis of bronchopulmonary dysplasia (BPD). Type 3 innate lymphoid cells (ILC3) play a role in a variety of inflammatory lung diseases. In this study, we established the BPD model by injecting lipo...
Correction to: KCNQ1OT1 Exacerbates Ischemia-Reperfusion Injury Through Targeted Inhibition of miR-140-3P [0.03%]
Correction to: KCNQ1OT1通过靶向抑制miR-140-3P加重缺血再灌注损伤
Ming Yi,Yue Li,Dan Wang et al.
Ming Yi et al.
Published Erratum
Inflammation. 2022 Apr;45(2):933-934. DOI:10.1007/s10753-022-01635-y 2022
Upregulation of Unfolded Protein Response and ER Stress-Related IL-23 Production in M1 Macrophages from Ankylosing Spondylitis Patients [0.03%]
强直性脊柱炎患者M1型巨噬细胞中未折叠蛋白反应和内质网应激相关IL-23产生的增加
Alireza Rezaiemanesh,Mahdi Mahmoudi,Ali Akbar Amirzargar et al.
Alireza Rezaiemanesh et al.
The inflammatory interleukin (IL)-23/IL-17 axis plays an important role in the pathogenesis of ankylosing spondylitis (AS), but with an unknown regulatory mechanism. This study aimed to investigate the role of endoplasmic reticulum (ER) str...
Polyene Phosphatidylcholine Interacting with TLR-2 Prevents the Synovial Inflammation via Inactivation of MAPK and NF-κB Pathways [0.03%]
聚烯基磷脂酰胆碱通过与TLR-2相互作用，使MAPK和NF-κB失活来防止滑膜炎症
Zixuan Xu,Wenting Hao,Daxiang Xu et al.
Zixuan Xu et al.
Rheumatoid arthritis (RA) is a chronic autoimmune joint disease that causes cartilage and bone damage or even disability, seriously endangering human health. Chronic synovial inflammation has been shown to play a vital role in disease susta...
Association of miR-155, miR-187 and Inflammatory Cytokines IL-6, IL-10 and TNF-α in Chronic Opium Abusers [0.03%]
miR-155、miR-187与慢性阿片类药物成瘾者中的炎症细胞因子IL-6、IL-10和TNF-α的相关性研究
Purvi Purohit,Dipayan Roy,Shailendra Dwivedi et al.
Purvi Purohit et al.
Substance use disorders are known to be associated with inflammation. However, the dynamics of inflammatory cytokines and microRNA in chronic opium use is yet unexplored. The current study determined the levels of inflammatory cytokines TNF...
Noncanonical Wnt5a/JNK Signaling Contributes to the Development of D-Gal/LPS-Induced Acute Liver Failure [0.03%]
非Canonical Wnt5a/JNK信号通路参与D-半乳糖/内毒素致急性肝衰竭小鼠模型发病机制中的作用研究
Xiang-Fen Ji,Yu-Chen Fan,Fei Sun et al.
Xiang-Fen Ji et al.
Acute liver failure (ALF) is a deadly clinical disorder with few effective treatments and unclear pathogenesis. In our previous study, we demonstrated that aberrant Wnt5a expression was involved in acute-on-chronic liver failure. However, t...
Mao-Qiang Man,Joan S Wakefield,Theodora M Mauro et al.
Mao-Qiang Man et al.
Nitric oxide (NO), a signaling molecule, regulates biological functions in multiple organs/tissues, including the epidermis, where it impacts permeability barrier homeostasis, wound healing, and antimicrobial defense. In addition, NO partic...
Human Breast Milk-Derived Exosomal miR-148a-3p Protects Against Necrotizing Enterocolitis by Regulating p53 and Sirtuin 1 [0.03%]
人乳外泌体来源的miR-148a-3p通过调节p53和Sirtuin 1对抗坏死性小肠结肠炎
Miao-Miao Guo,Kun Zhang,Jia-Hui Zhang
Miao-Miao Guo
Necrotizing enterocolitis (NEC) is a gastrointestinal disease that results in the exaggerated intestinal inflammation and injury. Human breast milk-derived exosome (BMEXO) has been reported to relieve NEC, which is closely related to the co...
Timothy Grass Pollen Induces Spatial Reorganisation of F-Actin and Loss of Junctional Integrity in Respiratory Cells [0.03%]
Timothy草花粉诱导呼吸道上皮细胞F肌动蛋白重分布和连接复杂破坏
Peta Bradbury,Aylin Cidem,Hadi Mahmodi et al.
Peta Bradbury et al.
Grass pollens have been identified as mediators of respiratory distress, capable of exacerbating respiratory diseases including epidemic thunderstorm asthma (ETSA). It is hypothesised that during thunderstorms, grass pollen grains swell to ...