PDK4 acts via hippo signaling to inhibit ferroptosis and reduce gemcitabine sensitivity in pancreatic cancer [0.03%]
PDK4通过Hippo信号传导作用抑制胰腺癌铁死亡并降低吉西他滨敏感性
Lei Jin,Meng Pan,Xiaolong Yuan et al.
Lei Jin et al.
Ferroptosis has been implicated in cancer chemo-resistance. The role of pyruvate dehydrogenase kinase 4 (PDK4) in gemcitabine-induced ferroptosis in Pancreatic Adenocarcinoma (PAAD) was investigated. Immunohistochemistry and RNA sequencing ...
DNMT3a mediates FSTL3 methylation to regulate trophoblast proliferation, migration and invasion [0.03%]
DNA甲基化转移酶DNMT3a介导FSTL3的甲基化调控滋养细胞的增殖、迁移和侵袭功能
Ning Wang,Xiujun Li,Yanyun Wang et al.
Ning Wang et al.
Correction: In-silico analysis of multi-pathway crosstalk inhibition of santamarin in hepatocellular carcinoma [0.03%]
订正：圣麻林抑制肝癌多种途径串扰的计算分析
Johra Khan,Ali Jaaen Seger,Salam Adil Ahmed et al.
Johra Khan et al.
Published Erratum
Journal of molecular histology. 2026 Apr 20;57(3):143. DOI:10.1007/s10735-026-10796-1 2026
The TRAF6-TXNIP-NLRP3 signaling axis regulates LPS-induced pyroptosis in glomerular podocytes [0.03%]
TRAF6-TXNIP-NLRP3信号轴调节LPS诱导的足细胞pyroptosis
Chunhua Ye,Hua Liu,Zhu Ming et al.
Chunhua Ye et al.
Circadian rhythm disruption affects cellular senescence through the BMAL1/CRY2/PER1 signaling pathway in periodontitis [0.03%]
生物钟紊乱通过BMAL1/CRY2/PER1信号通路影响牙周炎成纤维细胞衰老
ChaoHui Zheng,YuanYuan Li,YanLi Zhang et al.
ChaoHui Zheng et al.
Accelerated cellular senescence may be a key process in the progression of periodontitis, as it integrates the devastating effects of the major risk factors for periodontitis. Circadian rhythm disruption (CRD) affects the expression levels ...
Interplay between miR-21 and mTOR signaling in an experimental mouse model of polycystic ovary syndrome [0.03%]
miR-21和mTOR信号通路在多囊卵巢综合征小鼠模型中的相互作用研究
Sibel Demirci Delipinar,Hakan Ekmekci,Zeynep Banu Gungor et al.
Sibel Demirci Delipinar et al.
Polycystic ovary syndrome (PCOS), one of the leading causes of anovulatory infertility, is a complex endocrinopathy influenced by environmental factors. Evidence suggests a connection between PCOS and mammalian target of rapamycin (mTOR), a...
Effects of human umbilical cord derived mesenchymal stem cells transplantation on ovarian function in rats with ovarian hyperstimulation syndrome [0.03%]
人脐带间充质干细胞移植对卵巢过度刺激综合征模型大鼠卵巢功能的影响
Feride Özdemir,Sibel Köktürk,Serçin Karahüseyinoğlu et al.
Feride Özdemir et al.
Nell-1 inhibits osteoclast differentiation and bone resorption in apical periodontitis [0.03%]
nell-1抑制根尖周炎破骨细胞的分化及骨吸收作用
Chaoran Liang,Zhiyan Zhou,Mengyin Luan et al.
Chaoran Liang et al.
Apical periodontitis (AP) is characterized by progressive osteoclast-mediated bone destruction. Although Nell-1 may inhibit osteoclast differentiation, the underlying mechanisms and its specific role in AP remain unclear. This study aims to...
Effects of pirfenidone and fisetin on apoptosis and oxidative stress mechanisms in heart tissue of bleomycin-induced pulmonary fibrosis [0.03%]
吡非尼酮和山柰酚对博来霉素诱导肺纤维化心脏组织凋亡及氧化应激机制的影响
Ayşegül Burçin Yıldırım,Mehmet Göl,Leyla Çimen et al.
Ayşegül Burçin Yıldırım et al.
Bleomycin (BLM) is a chemotherapeutic agent that has been demonstrated to induce severe pulmonary and cardiac toxicity. Pirfenidone (PFD) is an established antifibrotic drug, while fisetin (FST) is a naturally occurring cardioprotective fla...
Protective effects of Pelargonium sidoides against oxidative stress and inflammation in experimental mesenteric ischemia-reperfusion injury [0.03%]
Pelargonium sidoides对实验性肠系膜缺血再灌注损伤氧化应激和炎症的保护作用
Simge Unay,Ferhat Sirinyildiz,Adem Keskin et al.
Simge Unay et al.
Pelargonium sidoides is traditionally used in South African herbal medicine for the treatment of respiratory tract infections and has been commercialized in over 50 countries as EPs® 7630. While most clinical applications focus on respirat...