Anti-inflammatory and protective effects of Aloe vera on intestinal function in zebrafish [0.03%]
芦荟对斑马鱼肠道功能的抗炎和保护作用
Qinghua Han,Suxi Xiao,Hao Wu et al.
Qinghua Han et al.
Aloe vera and its polysaccharides can reduce inflammation and support intestinal barrier repair, offering potential benefits for inflammatory bowel disease (IBD). Using a zebrafish model of TNBS-induced intestinal inflammation, we evaluated...
Targeting ACTG1 alleviates isoproterenol-induced cardiac injury by regulating endothelial-to-mesenchymal transition [0.03%]
靶向ACTG1通过调节内皮-间充质转化缓解异丙肾上腺素诱导的心脏损伤
Xianghui Zeng,Dian Wang,Hao Yang et al.
Xianghui Zeng et al.
The pathological mechanisms underlying cardiac fibrosis after isoproterenol (ISO)-induced cardiac injury remain poorly understood. Additionally, the biological function of ACTG1 in cardiovascular diseases has not been fully elucidated. This...
Inhibition of RBM25 preserves cardiac mitochondrial homeostasis and attenuates ischemic heart failure [0.03%]
抑制RBM25保护心脏线粒体稳态并减轻缺血性心力衰竭
Shu Liu,Hong Ding,Kejuan Li et al.
Shu Liu et al.
Heart failure (HF) after myocardial infarction (MI) is a serious complication that endangers the health of the patient. Mitochondrial dysfunction is an important mechanism in the development of ischemic HF. RNA-binding motif protein 25 (RBM...
GLSP ameliorates monocrotaline-induced pulmonary arterial hypertension through inhibition of the PI3K/AKT and MAPK signaling pathways [0.03%]
GLSP通过抑制PI3K/AKT和MAPK信号通路改善香豆素诱导的肺动脉高压
Yingying Wei,Siying Zuo,Na Deng et al.
Yingying Wei et al.
Pulmonary arterial hypertension (PAH) is characterized by pulmonary vascular remodeling and right heart dysfunction, driven largely by excessive proliferation of pulmonary arterial smooth muscle cells (PASMCs). The PI3K/AKT and MAPK signali...
Circ_0070190 suppresses the malignant progression of cervical cancer by sponging miR-587 [0.03%]
circ_0070190通过吸附mi r-587抑制宫颈癌恶性进展
Mingxia Lu,Yang Fan,Sanying Guo et al.
Mingxia Lu et al.
The purpose of this study is to explore the function of circ_0070190 in cervical cancer (CC) as well as its regulatory mechanism through sponging miR-587. RT-qPCR was applied to detect the expression of circ_0070190 and miR-587 in CC tissue...
Neuroprotective effects of myricetin against rotenone-ınduced parkinsonian neurotoxicity: a multidimensional analysis in rats [0.03%]
芦丁对罗虫毒素诱导的帕金森病神经毒性的影响：大鼠多维度分析中的神经保护作用
Onural Ozhan,Zehranur Erikci,Azibe Yildiz et al.
Onural Ozhan et al.
Parkinson's disease (PD) is a progressive neurodegenerative disorder characterized by dopaminergic neuronal loss, oxidative stress (OS), and α-synuclein pathology. As OS is a major contributor to neuronal injury in PD, therapeutic approach...
Retraction Note: The ameliorative effects of cinnamon oil against ethanol‑induced gastric ulcer in rats by regulating oxidative stress and promoting angiogenesis [0.03%]
撤回 notice:肉桂油通过调节氧化应激和促进血管生成缓解酒精诱导的大鼠胃溃疡的改善作用
Samraa Hussein Abdel-Kawi,Khalid Shaaban Hashem,Marina Kamel Saad et al.
Samraa Hussein Abdel-Kawi et al.
S100 signaling in hair follicle biology: emerging mechanistic insights and therapeutic opportunities [0.03%]
hair囊生物学中的S100信号：新兴的机制见解和治疗机会
Dongfan Wei,Hongwei Jia,Lin Shang et al.
Dongfan Wei et al.
S100 proteins are a conserved family of calcium-binding proteins that regulate diverse cellular processes across multiple tissues, with particularly important roles in skin biology. In the hair follicle (HF), different S100 members are expr...
S100 signaling in hair follicle biology: emerging mechanistic insights and therapeutic opportunities [0.03%]
毛囊生物学中S100信号转导：新机制研究见解和治疗机会
Dongfan Wei,Hongwei Jia,Lin Shang et al.
Dongfan Wei et al.
S100 proteins are a conserved family of calcium-binding proteins that regulate diverse cellular processes across multiple tissues, with particularly important roles in skin biology. In the hair follicle (HF), different S100 members are expr...
CO2-releasing hydrogels promote bone healing by activating transcription factor IRF1 to regulate HOXA2 [0.03%]
通过活化转录因子IRF1调节HOXA2促进骨修复的二氧化碳响应性水凝胶
Shiyou Dai,Li Feng,Xiao Fan et al.
Shiyou Dai et al.
Bone repair is a complex repair process involving various factors. Carbon dioxide (CO2) therapy has been shown to accelerate fracture repair and bone healing. The present study aimed to explore the effects of CO2-releasing hydrogels on oste...