Assessing Methods for Estimating Microbial Lag Phase Duration: A Comparative Analysis Using S.cerevisiae Empirical and Simulated Data [0.03%]
评估估算微生物迟滞期持续时间方法：使用S. cerevisae实证和模拟数据的比较分析
Monika Opalek,Dominika Wloch-Salamon,Bogna J Smug
Monika Opalek
The lag phase is a temporary, non-replicative period observed when a microbial population is introduced to a new, nutrient-rich environment. Although the theoretical concept of growth phases is clear, the practical application of methods fo...
Linking Endo-lysosomal pH, Sterol and Trafficking to Neurodegenerative Disease [0.03%]
连接溶酶体pH、固醇和转运与神经退行性疾病
Hari Prasad,Rajini Rao
Hari Prasad
Although endo-lysosomal abnormalities have been recognized as a pathognomonic feature of Alzheimer's disease, the lack of druggable targets has hampered the translation from bench to bedside. This article provides an overview of the insight...
Quorum Sensing in Saccharomyces cerevisiae Brewing Strains: Effects of 2-Phenylethanol on Proteomic, Lipidomic, and Metabolomic Profile [0.03%]
酿酒酵母菌株的群体感应：2-苯乙醇对蛋白质组、脂质组和代谢组的影响
Scott J Britton,Jonas Niemetz,Mirjam Haensel et al.
Scott J Britton et al.
Quorum sensing (QS) is a known mechanism by which microbial populations adjust gene expression and coordinate community-wide social behaviours based on the proximate population density. This regulatory system has garnered significant intere...
R Vasylyshyn,J Ruchala,K Dmytruk et al.
R Vasylyshyn et al.
The production of second-generation (2 G) bioethanol, a key sector in industrial biotechnology, addresses the demand for sustainable energy by utilizing lignocellulosic biomass. Efficient fermentation of all sugars from lignocellulose hydro...
Genomically integrated cassettes swapping: bringing modularity to the strain level in Saccharomyces cerevisiae [0.03%]
基因整合式置换：在毕赤酵母中实现分子模块化设计合成线路
Pietro Butti,Francesco Bellusci,Elisa Brambilla et al.
Pietro Butti et al.
A large variety of synthetic biology toolkits for the introduction of multiple expression cassettes is available for Saccharomyces cerevisiae. Unfortunately, none of these tools is designed to allow the modification-exchange or removal-of t...
Genetic and phenotypic diversity of wine-associated Hanseniaspora species [0.03%]
与葡萄酒相关的Hanseniaspora属物种的基因和表型多样性
Cristobal A Onetto,Chris Ward,Cristian Varela et al.
Cristobal A Onetto et al.
The genus Hanseniaspora includes apiculate yeasts commonly found in fruit- and fermentation-associated environments. Their genetic diversity and evolutionary adaptations remain largely unexplored despite their ecological and oenological sig...
Engineering of xylose metabolic pathways in Rhodotorula toruloides for sustainable biomanufacturing [0.03%]
工程改造解脂耶氏酵母木糖代谢途径用于可持续生物制造
Hyunjoon Oh,Hyun Gi Koh,Suk-Chae Jung et al.
Hyunjoon Oh et al.
The oleaginous yeast Rhodotorula toruloides is a promising microbial cell factory for the sustainable production of biofuels and value-added chemicals from renewable carbon sources. Unlike the conventional yeast Saccharomyces cerevisiae, R....
The genome of the polyextremophilic yeast, Naganishia friedmannii, reveals adaptations involved in stress response pathways, carbohydrate metabolism expansion, and a limited DNA repair repertoire [0.03%]
极端耐受酵母Naganishia friedmannii基因组揭示了参与胁迫响应途径、糖类代谢扩张和有限DNA修复的适应性
Lara Vimercati,Clifton P Bueno de Mesquita,Igor V Grigoriev et al.
Lara Vimercati et al.
Here we report the draft genome sequence of Naganishia friedmannii (formerly Cryptococcus friedmannii) isolate, a Basidiomycota yeast commonly found in some of the most extreme environments of the Earth's cryosphere. We isolated N. friedman...
The experimentally evolved fluconazole-resistant Clade II isolates of Candidozyma auris exhibit a distinct lipid compositional landscape, highlighting intra-clade sphingolipid heterogeneity [0.03%]
实验进化的氟康唑耐药白色念珠菌auris第二分支分离株表现出独特的脂质组分景观，突显了分支内的鞘脂异质性
Praveen Kumar,Basharat Ali,Mohit Kumar et al.
Praveen Kumar et al.
The intrinsic resistance of Candidozyma auris to antifungal drugs poses a major therapeutic challenge, with conventional resistance mechanisms providing only partial explanations. Sphingolipids (SLs), known for their interclade heterogeneit...
Molecular Evolution of the members of the Snq2/Pdr18 subfamily of Pdr transporters in the Hemiascomycete yeasts [0.03%]
汉雅ascus酵母菌Snq2 / Pdr18亚科Pdr转运蛋白成员的分子进化
Paulo Jorge Dias
Paulo Jorge Dias
The transporters of the ATP-Binding Cassette (ABC) Superfamily involved in the Multidrug Resistance (MDR) phenomena are also known as ABC Pleiotropic Drug Resistance (PDR) proteins. The homologs of the Saccharomyces cerevisiae SNQ2 and PDR1...