Nicholas R Robertson,Sangcheon Lee,Aida Tafrishi et al. Nicholas R Robertson et al.
CRISPR-Cas genome-wide screens are powerful tools for unraveling genotype-phenotype relationships, enabling precise manipulation of genes to study and engineer industrially-useful traits. Traditional genetic methods, such as random mutagene...
Functional analysis of Candida albicans Cdr1 through homologous and heterologous expression studies [0.03%] 通过同源和异源表达研究白色念珠菌Cdr1的功能分析
Mengcun Zhao,Erwin Lamping,Kyoko Niimi et al. Mengcun Zhao et al.
Candida albicans Cdr1 is a plasma membrane ATP-binding cassette transporter encoded by CDR1 that was first cloned 30 years ago in Saccharomyces cerevisiae. Increased expression of Cdr1 in C. albicans clinical isolates results in resistance ...
Image-based quantification of Candida albicans filamentation and hyphal length using the open-source visual programming language JIPipe [0.03%] 基于图像的白色念珠菌丝状生长和菌丝长度定量研究使用开源可视化编程语言JIPipe
Jan-Philipp Praetorius,Sophia U J Hitzler,Mark S Gresnigt et al. Jan-Philipp Praetorius et al.
The formation of hyphae is one of the most crucial virulence traits the human pathogenic fungus Candida albicans possesses. The assessment of hyphal length in response to various stimuli, such as exposure to human serum, provides valuable i...
Recent advances in genetic engineering and chemical production in yeast species [0.03%] 基因工程和酵母菌种化学生产的 recent advances 中文翻译为近期进展
Sangdo Yook,Hal S Alper Sangdo Yook
Yeasts have emerged as well-suited microbial cell factory for the sustainable production of biofuels, organic acids, terpenoids, and specialty chemicals. This ability is bolstered by advances in genetic engineering tools, including CRISPR-C...
Advancing Recombinant Protein Expression in Komagataella phaffii: Opportunities and Challenges [0.03%] Komagataella phaffii工程菌表达重组蛋白的机遇与挑战
Wen Lv,Menghao Cai Wen Lv
Komagataella phaffii has gained recognition as a versatile platform for recombinant protein production, with applications covering biopharmaceuticals, industrial enzymes, food additives, etc. Its advantages include high-level protein expres...
Aging Research Has Lost A Brilliant Investigator - Michael Breitenbach 1943 - 2024 [0.03%] 老龄化研究失去了一位杰出的研究人员——迈克尔·布雷滕巴赫 1943 - 2024
Ian W Dawes,Terrance G Cooper,Mark Rinnerthaler Ian W Dawes
Louise La Barbera Kastberg,Irene Hjorth Jacobsen,Emre Özdemir et al. Louise La Barbera Kastberg et al.
Yeast is a widely utilized chassis for heterologous protein production, with Komagataella phaffii well-established as a prominent non-conventional yeast in this field. Despite its widespread recognition, there remains considerable potential...
BAHD acyltransferase from dragon fruit enables production of phyllocactin in engineered yeast [0.03%] 仙人果BAHD酰基转移酶使合成酵母中生成PHYLLOCACTIN
Christiane Glitz,Jane Dannow Dyekjær,Sophia Mattitsch et al. Christiane Glitz et al.
Microbial fermentation can provide a sustainable and cost-effective alternative to traditional plant extraction to produce natural food colours. Betalains are a class of yellow to red water-soluble pigments. Even though over 80 betalain var...
Challenges in elucidating ethylene glycol metabolism in Saccharomyces cerevisiae [0.03%] 阐明乙二醇在酿酒酵母中的代谢机制面临的挑战
Vittorio Giorgio Senatore,Fiorella Masotti,Riccardo Milanesi et al. Vittorio Giorgio Senatore et al.
Polyethylene terephthalate (PET) is one of the most used polymers in the packaging industry; enzymatic recycling is emerging as a sustainable strategy to deal with waste PET, producing the virgin monomers terephthalic acid and ethylene glyc...
Comprehensive survey of kombucha microbial communities of diverse origins and fermentation practices [0.03%] 源自不同地区和发酵工艺的 kombucha 微生物群体的全面调查研究
Emna Ben Saad,Anne Friedrich,Frédérique Fischer et al. Emna Ben Saad et al.
Kombucha is a unique, naturally fermented sweetened tea produced for thousands of years, relying on a symbiotic microbiota in a floating biofilm, used for successive fermentations. The microbial communities consist of yeast and bacteria spe...