Fernanda Mariano Garcia,Valdemir Pereira de Sousa,Priscila Pinto E Silva-Dos-Santos et al.
Fernanda Mariano Garcia et al.
Asthma is a complex disease with varied clinical manifestations resulting from the interaction between environmental and genetic factors. While chronic airway inflammation and hyperresponsiveness are central features, the etiology of asthma...
Xinyu Zhang,Yian Zhou,Zheng Liu et al.
Xinyu Zhang et al.
Olfactory dysfunction (OD) can have serious consequences as it hinders individuals from detecting important warning signals like smoke, spoiled food, and gas leaks. This can significantly impact their nutritional status, eating satisfaction...
Group 3 Innate Lymphoid Cells: A Potential Therapeutic Target for Steroid Resistant Asthma [0.03%]
组3固有淋巴样细胞：治疗糖皮质激素抵抗型哮喘的潜在靶点
Marzhan Berkinbayeva,Wenjing Gu,Zhifeng Chen et al.
Marzhan Berkinbayeva et al.
Asthma is a chronic airway inflammatory disease that affects millions globally. Although glucocorticoids are a mainstay of asthma treatment, a subset of patients show resistance to these therapies, resulting in poor disease control and incr...
Regulatory Roles of SWI/SNF Chromatin Remodeling Complexes in Immune Response and Inflammatory Diseases [0.03%]
SWI/SNF染色质重塑复合体在免疫反应和炎症性疾病中的调控作用
Shunan Sun,Yu Chen,Yuzhen Ouyang et al.
Shunan Sun et al.
The switch/sucrose non-fermentable (SWI/SNF) chromatin remodeling complexes (also referred to as BAF complexes) are composed of multiple subunits, which regulate the nucleosome translocation and chromatin accessibility. In recent years, sig...
Advancements in the Study of the Immune Molecule NKp46 in Immune System-related Diseases [0.03%]
NKp46分子在免疫系统相关疾病研究中的进展
Siyi Qian,Yanhong Zhou,Zhongyuan Jin et al.
Siyi Qian et al.
NKp46 is a natural killer cell activating receptor primarily expressed on NK cells and non-NK innate lymphoid cells. In the context of anti-infection, NKp46 activates NK cells by binding to ligands on pathogens or infected cells, enabling N...
Hereditary Angioedema Attacks in Patients Receiving Long-Term Prophylaxis: A Systematic Review [0.03%]
长期预防性治疗患者的遗传性血管水肿发作：系统评价研究
Hilary J Longhurst,Mauro Cancian,Vesna Grivcheva-Panovska et al.
Hilary J Longhurst et al.
Long-term prophylaxis (LTP) has been shown to reduce the frequency of hereditary angioedema (HAE) attacks; however, attacks occurring in patients receiving LTP have not been well characterized. The objective of this systematic review was to...
A Novel Subset of Regulatory T Cells Induced by B Cells Alleviate the Severity of Immunological Diseases [0.03%]
新型的由B细胞诱导的调节性T细胞能够缓解免疫性疾病症状
Kuan-Hua Chu,Bor-Luen Chiang
Kuan-Hua Chu
Regulatory T (Treg) cells are crucial for maintaining immune tolerance by suppressing response to self-antigens and harmless antigens to prevent autoimmune diseases and uncontrolled immune responses. Therefore, using Treg cells is considere...
MDA5 Is a Major Determinant of Developing Symptoms in Critically Ill COVID-19 Patients [0.03%]
MDA5是危重COVID-19患者的疾病驱动因素及症状决定因素
Amit K Maiti
Amit K Maiti
Apart from the skin and mucosal immune barrier, the first line of defense of the human immune system includes MDA5 (ifih1 gene) which acts as a cellular sensor protein for certain viruses including SARS-CoV-2. Upon binding with viral RNA, M...
Non-allergic Hypersensitivity Reactions to Immunoglobulin Preparations in Antibody Deficiencies: What Role for Anti-IgA IgG and Complement Activation? [0.03%]
免疫球蛋白在抗体缺陷中的非过敏性超敏反应：抗IgA IgG和补体激活的作用？
Aurore Collet,Diane Pelletier de Chambure,Emmanuelle Moitrot et al.
Aurore Collet et al.
The presence of IgG anti-IgA in the serum of primary immunodeficiency (PID) patients has long been considered responsible for hypersensitivity (HS) to immunoglobulin preparations (IgPs), but this link is increasingly being questioned. The a...
Efficacy of Capsaicin for Non-allergic Rhinitis: An Updated Systematic Review and Meta-analysis [0.03%]
辣椒素治疗非过敏性鼻炎的疗效：系统回顾和荟萃分析更新
Jiatong Wang,Leilani Zhang,Kangyang Zheng
Jiatong Wang
Non-allergic rhinitis (NAR) is a prevalent condition with limited effective treatments. Capsaicin, an agonist of the transient receptor potential vanilloid subfamily 1 (TRPV1) receptor, has emerged as a potential therapeutic option for NAR ...