MDA5 Is a Major Determinant of Developing Symptoms in Critically Ill COVID-19 Patients
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Apart from the skin and mucosal immune barrier, the first line of defense of the human immune system includes MDA5 (ifih1 gene) which acts as a cellular sensor protein for certain viruses including SARS-CoV-2. Upon binding with viral RNA, MDA5 activates cell-i... ...
