A rare MYBL1-altered pediatric-type diffuse astrocytoma with positive OLIG2 and MAP2 expression and high proliferative activity [0.03%]
一种罕见的MYBL1改变型儿童弥漫性星形细胞瘤，表达OLIG2和MAP2且增殖活性高
Min Zhou,Junjie Yang,Zejun Duan et al.
Min Zhou et al.
Clinicopathologic characterization of a non-expansile, epilepsy-associated neocortical lesion with BRAF K601E mutation [0.03%]
具有BRAF K601E突变的与癫痫相关的新皮层非膨胀性病变的临床病理特征
Sangeetha Ramachandran,Ana E Berglind,Julien Hébert et al.
Sangeetha Ramachandran et al.
Spinal high-grade astrocytoma with piloid features presenting with progressive encephalopathy, hypoglycorrhachia, hydrocephalus, and leptomeningeal dissemination [0.03%]
以进行性脑病、低糖血症、脑积水和软脑膜扩散为表现的脊髓毛细胞星形细胞瘤伴皮洛伊德特征
Maximilian Mastall,Ramona-Alexandra Todea,Martin Zoche et al.
Maximilian Mastall et al.
An unusual extra-axial supratentorial presentation of atypical teratoid/rhabdoid tumor in a child [0.03%]
儿童不典型畸胎样/横纹肌样瘤的特殊病例报告
Vich Yindeedej,Putch Phairintr,Ploy Wisetsathon et al.
Vich Yindeedej et al.
Primary intracranial sarcoma, DICER1-mutant: 5 cases highlighting variable clinical and molecular features [0.03%]
Dicer1突变原发性颅内肉瘤：5例具有临床及分子特征多样的病例报告
Catherine K Gestrich,Simmi Patel,Seema M Shroff et al.
Catherine K Gestrich et al.
Primary intracranial sarcoma, DICER1-mutant, a novel, rare entity in the 2021 WHO classification of central nervous system tumors, is characterized by spindled to pleomorphic cells with eosinophilic cytoplasmic globules, immunophenotypic ev...
Anina Fiocchi,Elisabeth J Rushing,Simone Brandt et al.
Anina Fiocchi et al.
Comprehensive clinicomolecular characterization of a methylation-defined supratentorial high-grade astrocytoma with piloid features in a young adult with confirmed germline NF1 mutation [0.03%]
确认存在NF1种系突变的年轻成人具皮样特征的高度弥漫性脑干胶质瘤的全面临床分子特征分析
Matthieu Pallandre,Maroa Dridi,Wafa Bouleftour et al.
Matthieu Pallandre et al.
Spatial mapping, isolation, and culture of primary human microglia and astrocytes: A systematic review and framework for glial cell-based models [0.03%]
人脑微胶质细胞和星形胶质细胞的空间定位、分离及培养：系统性综述与基于神经胶质细胞的模型构架框架
Swatantra Kumar,Jahnavi Singh,Vimal K Maurya et al.
Swatantra Kumar et al.
Microglia and astrocytes are essential glial cells in the CNS that play key roles in brain development, homeostasis, and disease. While immortalized cell lines are convenient, they lack the physiological relevance of primary cells, highligh...
Multiparameter flow cytometry of CSF identifies elevated CD8+ effector memory and TEMRA T-cells in immune-mediated neurologic disorders [0.03%]
多参数脑脊液流式细胞术检测自身免疫介导性神经疾病中效应记忆T细胞及TEMRA T细胞增多
Danwei Wu,Samuel Zhang,Yaseen Ali Jamal et al.
Danwei Wu et al.
Conventional CSF markers often fail to distinguish immune-mediated neurologic disorders (IMNDs) from non-immune-mediated neurologic disorders (N-IMNDs). We performed multiparametric flow cytometric profiling of CSF T-cell developmental subs...
Comprehensive identification of FoxO signaling as a promising prognostic and immunotherapeutic biomarker in glioma [0.03%]
FoxO信号通路作为胶质瘤预后和免疫治疗生物标志物的全面鉴定
Yuetao Wen,Ya He,Jingang Li et al.
Yuetao Wen et al.
Convincing evidence suggests that FoxO signaling (FS) dysfunction is associated with cancer progression and tumorigenesis but its effect on the tumor microenvironment (TME) and immunotherapy response remains unclear. Here, we retrieved FS-r...