Knockdown of TRIM21 inhibits ferroptosis via the p62-Keap1-Nrf2 pathway thereby improving brain injury and mitochondrial dysfunction after ischemia-reperfusion in mice
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Ferroptosis has a crucial role in cerebral ischemia-reperfusion injury (IRI) but its potential modulation is a key challenge in the treatment of ischemic stroke. The function and mechanism of the E3 ubiquitin ligase tripartite motif-containing protein 21 (TRIM... ...
