In Vitro Evaluation of Periodontal Fibroblast Response to Bioinspired Porous Channel-Embedded Zirconia Surfaces [0.03%]
仿生多孔通道羟基磷灰石增强氧化锆表面的牙周纤维细胞响应体外评价
Joana Ribeiro,Manuela Proença,Flávio Rodrigues et al.
Joana Ribeiro et al.
Customized implant approaches are emerging to meet specific patient needs while minimizing complications. Despite advances in osseointegrated implants, issues such as excessive bone loading, bacterial infiltration, peri-implantitis, and bon...
Biomimetic Gelatin-Based 3D Scaffolds for Enhanced Islet Microencapsulation and Functionality in Diabetes Therapy [0.03%]
用于糖尿病治疗的仿生明胶基三维支架以增强胰岛微囊化和功能
Rukhiya Salim,P S Unnikrishnan,D A Arya et al.
Rukhiya Salim et al.
Tissue-engineered scaffolds are increasingly important for improving pancreatic islet transplantation, as conventional transplantation disrupts the pancreas's native vasculature and extracellular matrix, reducing islet viability and functio...
Synthetic Mechanogenetic Gene Circuit Response in Human Induced Pluripotent Stem Cell-Derived Chondrocytes Is Altered by Matrix Stiffness [0.03%]
基质刚度改变人诱导多能干细胞来源软骨细胞合成机械遗传基因电路反应
Yu Seon Kim,Autumn Kim,Nancy Steward et al.
Yu Seon Kim et al.
Transient receptor potential vanilloid 4 (TRPV4) is a mechanosensitive ion channel found in both excitatory and non-excitatory cells in the body. In chondrocytes, TRPV4 plays a crucial role in transducing physiologic levels of mechanical lo...
Spinel-Structured MnCo2O4 Nanoclusters Mediate Multimodal and Efficient Suppression of Drug-Resistant Bacteria [0.03%]
尖晶石型MnCo₂O₄纳米簇介导多模态高效耐药细菌抑制效应
Guanlin Wu,Lizhong Wu,Yajie Zheng et al.
Guanlin Wu et al.
The global dissemination of bacterial antibiotic resistance has emerged as a formidable public health challenge. According to the World Health Organization (WHO), drug-resistant infections claim over 1.3 million lives annually, with project...
Innovations in Implant Osseointegration: Biomaterials, Surface Engineering, and Translational Strategies [0.03%]
植入物骨整合创新技术：生物材料、表面工程和转化策略
Yujin Ahn,Purva K Desai,Anna Rainey et al.
Yujin Ahn et al.
Osseointegration is critical for the long-term success of orthopedic and dental implants. This review highlights the biological mechanisms underlying bone-implant integration and recent advances in bioactive materials, drug delivery systems...
Lidocaine-TiO2 Composite Coating for Chest Tubes: Modulating Sustained Drug Release, Antiadhesive Performance, and Antibacterial Properties [0.03%]
利多卡因-二氧化钛复合涂层胸管：调节持续药物释放，防粘连性能和抗菌性能
Yutong Ding,Qianyun Zhang,Mian Xu et al.
Yutong Ding et al.
Chest tubes used in cardiothoracic surgery must meet critical clinical requirements, including effective analgesia, inhibition of protein adhesion, and prevention of infection. In this study, a dual-layered coating was developed, comprising...
Localized Antiadhesive Hydrogel Barriers for Prevention of Postoperative Adhesion [0.03%]
用于术后粘连预防的局部抗粘附水凝胶屏障
Hiyori Komatsu,Shiharu Watanabe,Kazuhiro Nagasaka et al.
Hiyori Komatsu et al.
Postoperative adhesions are frequent and serious complications that lead to longer operative times and high medical costs. Various types of antiadhesive materials, including films, solutions, and hydrogels, have been developed; however, the...
Surface-Modified Electrospun Polyurethane Tubular Scaffold for Engineering Renal Proximal Tubule Constructs [0.03%]
表面修饰的电纺聚氨酯管状支架用于工程肾近曲小管组织构建
Anjali Sudha,Amrita Natarajan,Kyra A Ramirez et al.
Anjali Sudha et al.
The renal proximal tubule (PT) is central to kidney physiology and is particularly susceptible to injury; however, in vitro systems that accurately replicate its microenvironment and functional characteristics remain limited. To address thi...
Comparing Collagen and Decellularized Extracellular Matrix in Different Fabrication Contexts for Bladder Tissue Engineering [0.03%]
不同制备条件下的胶原蛋白和脱细胞基质在膀胱组织工程中的比较研究
Ehsan Heidarian,Mohammad Naji,Rasool Setareyi et al.
Ehsan Heidarian et al.
Biomaterials demonstrate significantly different properties based on their fabrication methods, which must be considered for their intended applications. This study compares collagen and decellularized extracellular matrix (dECM) as sponge ...
Evolving Transport Properties of Dynamic Hydrogels Enable Self-Tuning of Short- and Long-Term Cargo Delivery [0.03%]
可演变的运输性质动态水凝胶实现短期和长期货物递送的自我调节
Samya Sen,Changxin Dong,Carolyn K Jons et al.
Samya Sen et al.
Modulating Cargo Release Using Time-evolving Hydrogels. Hydrogels are crosslinked polymer networks with h...