Synthetic Mechanogenetic Gene Circuit Response in Human Induced Pluripotent Stem Cell-Derived Chondrocytes Is Altered by Matrix Stiffness
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Transient receptor potential vanilloid 4 (TRPV4) is a mechanosensitive ion channel found in both excitatory and non-excitatory cells in the body. In chondrocytes, TRPV4 plays a crucial role in transducing physiologic levels of mechanical loading and osmotic st... ...
