The Reparative Ability of the Aligned Decellularized Annulus Fibrosus Matrix/Poly(Ether Carbonate Urethane)Urea Blended Fibrous Scaffolds on Annulus Fibrosus Defects [0.03%]
取向脱细胞纤维环基质/聚醚碳酸酯尿素共混纤维支架修复纤维环缺损的修复能力研究
Yifeng Li,Yu Zhang,Chen Liu
Yifeng Li
Currently, there is a lack of effective methods to repair annulus fibrosus (AF) defects in clinical practice. Therefore, exploring strategies to promote AF regeneration is of significant importance for delaying intervertebral disc degenerat...
Design and Manufacturing of Multifunctional Hydroxyapatite-Coated Ti6Al4V Implants With Cissus quadrangularis [0.03%]
以Cissus quadrangularis设计并制造的多种功能型羟基磷灰石涂覆钛合金植入体
Susmita Bose,Samuel F Robertson,Priya Kushram et al.
Susmita Bose et al.
This study presents a novel approach to enhance the early-stage osseointegration of orthopedic implants through surface engineering. Lithium (Li), strontium (Sr), and silver (Ag)-doped hydroxyapatite (HA) were coated on Ti6Al4V substrates u...
Impact of Leaflet Thickness on Polymeric Valve Scaffold Function and Remodeling: Assessment in a 1- and 3-Month Ovine Stented Pulmonary Valve Replacement Model [0.03%]
叶瓣厚度对聚合物瓣膜支架功能和重塑的影响：评估于绵羊肺动脉瓣置换模型中1个月和3个月的情况
Drake D Pedersen,Garrett Coyan,Viktor Balashov et al.
Drake D Pedersen et al.
Approaches to the structural design of tissue engineered heart valves (TEHVs) have varied broadly, ranging from material choice to microstructural and macro-scale functional characteristics. Not only will each variable on this extensive lis...
Integrating Near-Field Direct-Writing 3D Printing and Layer-By-Layer Self-Assembly to Construct Electroactive Anisotropic Scaffolds for Neural Tissue Engineering [0.03%]
结合近场直写三维打印和层层自组装构建用于神经组织工程的电活性各向异性支架
Chao Shen,Baiheng Lv,Yujun Zeng et al.
Chao Shen et al.
All current clinical treatments for peripheral nerve injury (PNI), including end-to-end suturing, allografts, non-surgical management, and autografts, suffer from inherent limitations that prevent adequate functional recovery. To address th...
Bioinspired Integrated MgH2 Hydrogel Synergistically Modulates the Osteo-Immune Microenvironment for Enhanced Bone Repair [0.03%]
仿生集成镁氢化物水凝胶协同调节成骨免疫微环境以增强骨修复
Rui Huang,Zhonghua Yang,Miao Wang et al.
Rui Huang et al.
Magnesium-based biomaterials show great potential in bone regeneration due to their inherent biocompatibility, osteogenic activity, and ability to modulate the immune microenvironment. However, their rapid degradation rate remains a critica...
Concentration-Dependent Effects of Carboxymethyl Chitosan-rGO Scaffolds for Oral Bone Regeneration [0.03%]
基于浓度的果胶甲基壳聚糖-rgo支架在口腔骨组织再生中的作用研究
Ronghui Zhou,Yanjun Lin,Xiaojing Zhu et al.
Ronghui Zhou et al.
To address alveolar bone defects and the limitations of conventional grafts, tissue-engineered scaffolds have emerged as a promising alternative. Carboxymethyl chitosan (CMC) is a biocompatible and biodegradable polysaccharide with potentia...
Hyaluronidase-Responsive MSN-HA Coatings for Infection-Triggered Antibiotic Delivery on Titanium Surfaces [0.03%]
一种用于钛表面感染响应型载药的透明质酸分解酶响应MSN-HA涂层抗菌体系
Merve Yolum,Sakip Önder
Merve Yolum
Implant-associated infections remain a major challenge due to biofilm formation and uncontrolled antibiotic release from conventional coatings. This study presents an enzyme-responsive nanoparticle-based coating designed to enable localized...
Silk Fibroin and Gelatin Immobilization on Poly(Caprolactone) Nonwoven Mats via Carbodiimide Coupling and Electrostatic Layer-By-Layer Deposition: Characterization and Cell Growth [0.03%]
碳二亚胺偶联和静电逐层沉积在聚己内酯非织造布上固定丝素蛋白和明胶：表征及细胞生长研究
Oliwia Jeznach,Onur Hasturk,Dorota Kołbuk et al.
Oliwia Jeznach et al.
Surface modification of scaffolds is a topic of great interest in tissue engineering due to the crucial role of scaffold surface in interactions with cells. In this study, we characterize electrospun poly(caprolactone) (PCL) nonwoven mats c...
Effects of Poly(β-Amino Ester) Networks on Macrophage Response In Vitro [0.03%]
聚β-氨基酯网络的网状结构对巨噬细胞反应的影响作用
Kayla Castillo-Aguilar,Aiden Walter,Stephanie J Bryant
Kayla Castillo-Aguilar
Poly(β-amino ester) or PBAE-based polymer networks are promising degradable biomaterials. This work investigated PBAEs formed from PBAE-diacrylate (PBAE-dA) macromers to assess how network chemistry and structure impact macrophages. PBAE-d...
Microgel-Based Immunomodulatory Biomaterials for Regulating Macrophage Polarization [0.03%]
基于微凝胶的免疫调控生物材料调节巨噬细胞极化
Cody Tuftee,Muhammad Rizwan
Cody Tuftee
Microgel-based biomaterials have gained increasing attention for their ability to modulate the immune response by regulating macrophage polarization, a key determinant in the transition from inflammation to tissue regeneration. Among these,...