Mesenchymal Stem Cells and Empagliflozin: a potential therapeutic approach for autophagy and Klotho modulation in Diabetic Kidney Disease [0.03%]
间充质干细胞与恩格列净：在糖尿病肾脏疾病中调节自噬和类固醇的潜在治疗手段
Marcella L Franco,Stephany Beyerstedt,Bruno S Barbosa et al.
Marcella L Franco et al.
Diabetic kidney disease (DKD), the leading cause of end-stage renal disease, involves injury across multiple renal compartments. Autophagy dysregulation is a key pathogenic mechanism and may reduce Klotho, a renoprotective protein diminishe...
Vacuolar protein sorting 4B is a novel regulator of osteoblast and adipocyte differentiation by activating autophagy signaling [0.03%]
溶酶体蛋白分选受体4B通过激活自噬信号促进成骨细胞和脂肪细胞分化
Jinyu Ma,Xingli Hu,Xinfeng Liu et al.
Jinyu Ma et al.
Vacuolar protein sorting 4B (VPS4B) is part of the endosomal sorting complex required for the transport (ESCRT) machinery and is essential for autophagosome completion. Vps4b mutation might reduce the ability of dental follicle cells to dif...
Engineering Neural Organoids: Technological Advances and Translational Frontiers [0.03%]
工程化类器官：技术前沿与转化机遇
Sungmin Kim,Hye-Ju Jo,Sung-Hwan Moon
Sungmin Kim
Neural organoids have transformed experimental neuroscience by enabling human-specific models of brain development, function, and disease. Emerging at the intersection of stem cell biology and tissue engineering, these self-organizing syste...
MSC-derived small extracellular vesicles promote dental pulp repair by alleviating inflammation in pulpitis via AKT and p38 MAPK pathways [0.03%]
牙髓炎中MSC来源的小细胞外囊泡通过AKT和p38MAPK通路缓解炎症促进牙髓修复
Jiajun Shi,Yuanyuan Jiang,Shipin Zhang et al.
Jiajun Shi et al.
Background: Pulpitis compromises dental pulp defense and repair, and current therapies inadequately resolve inflammation. Mesenchymal stem/stromal cell (MSC)-derived small extracellular vesicles (sEVs) exhibit potent anti...
Human iPSC-Derived 3D Cardiac Models for Cardiomyopathies: Organoids, Spheroids, and Engineered Heart Tissues as Translational Platforms [0.03%]
人多能干细胞来源的三维心脏模型在心肌病中的应用：类器官、球体和工程化心肌组织作为转化平台
Prabin Upadhyaya
Prabin Upadhyaya
Cardiomyopathies represent a substantial global health burden, yet progress in developing effective therapies was long constrained by the absence of physiologically relevant human models to understand molecular mechanisms and evaluating int...
Correction to: Mitochondrial Transfer from Mesenchymal Stem Cells to Macrophages Restricts Inflammation and Alleviates Kidney Injury in Diabetic Nephropathy Mice via PGC-1α Activation [0.03%]
Correction to：间充质干细胞线粒体转移通过激活PGC-1α限制糖尿病肾病小鼠炎症和减轻肾脏损伤机制研究
Published Erratum
Stem cells (Dayton, Ohio). 2026 Jun 27;44(7):sxag031. DOI:10.1093/stmcls/sxag031 2026
Correction to: Critical role of the potential O-linked glycosylation sites of CXCR4 in cell migration and bone marrow homing of hematopoietic stem progenitor cells [0.03%]
correction: cxcr4天冬酰胺残基的o-连接糖基化修饰在造血干细胞迁移和归巢中的作用
Published Erratum
Stem cells (Dayton, Ohio). 2026 Jun 27;44(7):sxag030. DOI:10.1093/stmcls/sxag030 2026
Loic P Deleyrolle
Loic P Deleyrolle
CircVapa promotes the abnormal differentiation of small intestinal epithelial stem cells in diabetic state [0.03%]
CircVapa促进糖尿病状态下小肠上皮干细胞分化异常
Ti-Dong Shan,Wen-Jing Feng,Li Chen
Ti-Dong Shan
Diabetic enteropathy (DE) is a common complication of diabetes mellitus (DM), yet its underlying molecular mechanisms remain poorly understood. Emerging evidence suggests that abnormal differentiation of intestinal epithelial stem cells (IE...