Physiology in Perspective [0.03%]
从宏观角度谈生理学
Christopher England
Christopher England
From Beats to Metabolism: the Heart at the Core of Interorgan Metabolic Cross Talk [0.03%]
从心律到代谢：心脏在器官间代谢交流中的核心作用
Rafael Romero-Becera,Ayelén M Santamans,Alba C Arcones et al.
Rafael Romero-Becera et al.
The heart, once considered a mere blood pump, is now recognized as a multifunctional metabolic and endocrine organ. Its function is tightly regulated by various metabolic processes, at the same time it serves as an endocrine organ, secretin...
Willis Rick Samson,Dee Silverthorn,Timothy Musch
Willis Rick Samson
Jung Dae Kim,Francesca Copperi,Sabrina Diano
Jung Dae Kim
Beyond their role as brain immune cells, microglia act as metabolic sensors in response to changes in nutrient availability, thus playing a role in energy homeostasis. This review highlights the evidence and challenges of studying the role ...
Physiological Functions of the Ubiquitin Ligases Nedd4-1 and Nedd4-2 [0.03%]
泛素连接酶Nedd4-1和Nedd4-2的生理功能
Daniela Rotin,Gali Prag
Daniela Rotin
The Nedd4 family of E3 ubiquitin ligases, consisting of a C2-WW(n)-HECT domain architecture, includes the closely related Nedd4/Nedd4-1 and Nedd4L/Nedd4-2, which play critical roles in human physiology and pathophysiology.This review focuse...
Audrey Mat,Hong Ha Vu,Eva Wolf et al.
Audrey Mat et al.
One of the biggest environmental alterations we have made to our species is the change in the exposure to light. During the day, we typically sit behind glass windows illuminated by artificial light that is >400 times dimmer and has a very ...
Endothelium-Derived Dopamine and 6-Nitrodopamine in the Cardiovascular System [0.03%]
心血管系统中的内皮多巴胺及6-硝基多巴胺
Roberto Zatz,Gilberto De Nucci
Roberto Zatz
The review deals with the release of endothelium-derived dopamine and 6-nitrodopamine (6-ND) and its effects on isolated vascular tissues and isolated hearts. Basal release of both dopamine and 6-ND is present in human isolated umbilical co...
Physiology in Perspective [0.03%]
从宏观角度理解生理学
Christopher England
Christopher England
Sandra M Sancho-Martínez,Francisco J López-Hernández
Sandra M Sancho-Martínez
Acute kidney frailty is a premorbid condition of diminished renal functional reserve that predisposes to acute kidney injury; this condition results from subclinical wear or distortion of renal homeostatic responses that protect the renal e...
Craig R White,Dustin J Marshall
Craig R White
Most explanations for the relationship between body size and metabolism invoke physical constraints; such explanations are evolutionarily inert, limiting their predictive capacity. Contemporary approaches to metabolic rate and life history ...