Two Pulses Per Beat: Parallel Energetics of Myocardium and Coronary Wall [0.03%]
两次脉冲一次心跳：心肌和冠状动脉壁的并行能量代谢
Manuel F Muñoz,L Fernando Santana
Manuel F Muñoz
Each heartbeat is initiated by a sinoatrial node action potential that propagates through the myocardial syncytium, triggering sequential contraction of the four chambers and propelling blood through the coronary, pulmonary, and systemic ci...
Amanda Heidt
Amanda Heidt
Dietary modulation of CMA: implications for cancer prevention and therapy [0.03%]
饮食调节无处不在的蛋白酶CMA：癌症预防和治疗的潜在策略
Cecilia Sanchez-Felipe,Esperanza Arias,Julio Madrigal-Matute
Cecilia Sanchez-Felipe
Chaperone-mediated autophagy (CMA) is a selective lysosomal degradation pathway that links nutrient availability to intracellular proteostasis through the targeted turnover of selective cytosolic proteins. Through this selective control of ...
Michaela Keuper,Martin Jastroch
Michaela Keuper
Endothermy depends on the ability to generate heat beyond basal metabolic output. The transition from incidental metabolic heat production to regulated adaptive thermogenesis represents a critical, yet poorly understood milestone in vertebr...
The Iron Lung: Ferroptosis and Iron Regulation in Aging and Lung Diseases [0.03%]
“铁肺：衰老和肺部疾病的铁死亡与铁代谢调控”
Maunick Lefin Koloko Ngassie,Yamillie Ortiz,Preetham Ravi et al.
Maunick Lefin Koloko Ngassie et al.
Iron is an important metal element regulating biological processes such as gene expression, electron transport, cell proliferation, differentiation and division, and cellular respiration. Regulation of iron levels is therefore critical, wit...
Kaito Masaki,Malvin Leonardo Pardi,Hirohide Saito
Kaito Masaki
RNA-protein interaction forms an important part of gene expression control in the form of post-transcriptional regulation. It affects key cellular processes, including cell fate-determining events such as self-renewal and differentiation of...
Ion Channels as Gatekeepers of Fertility: From Uterine Kir7.1 to Sperm CatSper [0.03%]
离子通道：生殖之门——从子宫Kir7.1到精子CatSper
Qingwei Niu,Polina V Lishko
Qingwei Niu
Karen L Sweazea
Karen L Sweazea
Insulin is an evolutionarily conserved peptide hormone best known for regulating glucose homeostasis, yet its physiological roles extend well beyond glucose regulation. Across the animal kingdom, insulin signaling influences such diverse ph...
Physiology in Perspective [0.03%]
生理学概论
Amanda Heidt
Amanda Heidt
Letter to the Editor: practical follow up to foundation models article [0.03%]
致编辑的信：关于基础模型文章的实践后续建议
Ryan C Godwin,Kameshwari Soundararajan,Ryan L Melvin
Ryan C Godwin