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期刊名:Nature structural & molecular biology

缩写:NAT STRUCT MOL BIOL

ISSN:1545-9993

e-ISSN:1545-9985

IF/分区:10.1/Q1

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Transcription at most promoters is divergent, initiating at closely spaced oppositely oriented core promoters to produce sense transcripts along with often unstable upstream antisense transcripts (uasTrx). How antisense transcription is reg...
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Lipids play important roles in regulating membrane protein function, but the molecular mechanisms used are elusive. Here we investigated how anionic lipids modulate SthK, a bacterial pacemaker channel homolog, and HCN2, whose activity contr...
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The addition of poly(UG) ('pUG') repeats to 3' termini of mRNAs drives gene silencing and transgenerational epigenetic inheritance in the metazoan Caenorhabditis elegans. pUG tails promote silencing by recruiting an RNA-dependent RNA polyme...
Mehmet Akdel,Douglas E V Pires,Eduard Porta Pardo et al. Mehmet Akdel et al.
Most proteins fold into 3D structures that determine how they function and orchestrate the biological processes of the cell. Recent developments in computational methods for protein structure predictions have reached the accuracy of experim...