H4S47 O-GlcNAcylation regulates the activation of mammalian replication origins [0.03%]
O-GlcNAc糖基化调节哺乳动物复制起点的激活
Yingying Zou,Jiayao Pei,Haizhen Long et al.
Yingying Zou et al.
The transmission and maintenance of genetic information in eukaryotic cells relies on the faithful duplication of the entire genome. In each round of division, excessive replication origins are licensed, with only a fraction activated to gi...
Katarzyna Ciazynska
Katarzyna Ciazynska
Dimitris Typas
Dimitris Typas
Takashi Ishikawa
Takashi Ishikawa
MAVS deSUMOylation by SENP1 inhibits its aggregation and antagonizes IRF3 activation [0.03%]
SENP1对MAVS去SUMO化抑制其聚集及拮抗IRF3活化功能的作用机制研究
Tong Dai,Lei Zhang,Yu Ran et al.
Tong Dai et al.
Mitochondrial antiviral signaling protein (MAVS) is an adapter that recruits and activates IRF3. However, the mechanisms underpinning the interplay between MAVS and IRF3 are largely unknown. Here we show that small ubiquitin-like modifier (...
Molecular basis of the TRAP complex function in ER protein biogenesis [0.03%]
_TRAP复合体在内质网蛋白质生物发生中的作用的分子机制
Mateusz Jaskolowski,Ahmad Jomaa,Martin Gamerdinger et al.
Mateusz Jaskolowski et al.
The translocon-associated protein (TRAP) complex resides in the endoplasmic reticulum (ER) membrane and interacts with the Sec translocon and the ribosome to facilitate biogenesis of secretory and membrane proteins. TRAP plays a key role in...
Author Correction: Smc5/6 silences episomal transcription by a three-step function [0.03%]
作者更正：Smc5/6通过三步功能沉默外源质粒的转录
Fabien Abdul,Aurélie Diman,Bastien Baechler et al.
Fabien Abdul et al.
Published Erratum
Nature structural & molecular biology. 2023 Jun;30(6):860. DOI:10.1038/s41594-023-01009-4 2023
Johannes Rudolph,Karolin Luger
Johannes Rudolph
Structural basis of metabolite transport by the chloroplast outer envelope channel OEP21 [0.03%]
叶绿体外膜通道蛋白OEP21的代谢物转运结构基础
Umut Günsel,Kai Klöpfer,Elisabeth Häusler et al.
Umut Günsel et al.
Triose phosphates (TPs) are the primary products of photosynthetic CO2 fixation in chloroplasts, which need to be exported into the cytosol across the chloroplast inner envelope (IE) and outer envelope (OE) membranes to sustain plant growth...