Jongdae Won,Jinhyeong Kim,Jinsung Kim et al.
Jongdae Won et al.
Transient receptor potential (TRP) ion channels have a crucial role as cellular sensors, mediating diverse physical and chemical stimuli. The formation of heteromeric structures expands the functionality of TRP channels; however, their mole...
Publisher Correction: Structure and activation of the RING E3 ubiquitin ligase TRIM72 on the membrane [0.03%]
出版更正：膜上RING E3泛素连接酶TRIM72的结构和激活形式
Si Hoon Park,Juhyun Han,Byung-Cheon Jeong et al.
Si Hoon Park et al.
Published Erratum
Nature structural & molecular biology. 2024 Nov;31(11):1810. DOI:10.1038/s41594-024-01429-w 2024
Author Correction: Structural basis for antibody-mediated NMDA receptor clustering and endocytosis in autoimmune encephalitis [0.03%]
作者更正：自身免疫性脑炎中抗体介导的N-甲基-D-天冬氨酸受体聚集和内吞的结构基础
Han Wang,Chun Xie,Bo Deng et al.
Han Wang et al.
Published Erratum
Nature structural & molecular biology. 2024 Nov;31(11):1809. DOI:10.1038/s41594-024-01410-7 2024
DNA methylation shapes the Polycomb landscape during the exit from naive pluripotency [0.03%]
DNA 甲基化在 naïve 多能性退出过程中的染色质修饰重塑作用
Julien Richard Albert,Teresa Urli,Ana Monteagudo-Sánchez et al.
Julien Richard Albert et al.
In mammals, 5-methylcytosine (5mC) and Polycomb repressive complex 2 (PRC2)-deposited histone 3 lysine 27 trimethylation (H3K27me3) are generally mutually exclusive at CpG-rich regions. As mouse embryonic stem cells exit the naive pluripote...
Kyle R Barrie,Grzegorz Rebowski,Roberto Dominguez
Kyle R Barrie
Gelsolin is the prototypical member of a family of Ca2+-activated F-actin severing and capping proteins. Here we report structures of Ca2+-bound human gelsolin at the barbed end of F-actin. One structure reveals gelsolin's six domains (G1G6...
Noopur Singh,Erik Johansson
Noopur Singh
Membrane structure-responsive lipid scrambling by TMEM63B to control plasma membrane lipid distribution [0.03%]
TMEM63B感应质膜结构的脂类打散作用以调控质膜脂质分布
Yugo Miyata,Katsuya Takahashi,Yongchan Lee et al.
Yugo Miyata et al.
Phospholipids are asymmetrically distributed in the plasma membrane (PM), with phosphatidylcholine and sphingomyelin abundant in the outer leaflet. However, the mechanisms by which their distribution is regulated remain unclear. Here, we sh...
Mechanism of polyadenylation-independent RNA polymerase II termination [0.03%]
独立于多腺苷酸化的RNA聚合酶II终止机制
Srinivasan Rengachari,Thomas Hainthaler,Christiane Oberthuer et al.
Srinivasan Rengachari et al.
The mechanisms underlying the initiation and elongation of RNA polymerase II (Pol II) transcription are well-studied, whereas termination remains poorly understood. Here we analyze the mechanism of polyadenylation-independent Pol II termina...
Time-course remodeling and pathology intervention of α-synuclein amyloid fibril by heparin and heparin-like oligosaccharides [0.03%]
肝素和类似寡糖对α-突触核蛋白淀粉样纤维重塑及病理干预的动态过程研究
Youqi Tao,Peng Xu,Shenqing Zhang et al.
Youqi Tao et al.
Amyloid fibrils represent a pathological state of protein polymer that is closely associated with various neurodegenerative diseases. Polysaccharides have a prominent role in recognizing amyloid fibrils and mediating their pathogenicity. Ho...