An Innovative Diagnostic Strategy for Malignant Pleural Effusion Using Discontinuous Gradient Centrifugation [0.03%]
Jin-Xin Zhu,Lei Yuan,Yong-Tao Zhan et al.
Jin-Xin Zhu et al.
Context.—: Malignant pleural effusion (MPE) is a common cancer metastatic complication, and distinguishing it from benign effusions is critical for treatment. Cytology is central to MPE diagnosis, but inflammatory and re...
Diagnostic Utility of Dysmorphic Erythrocyte Identification Using the Atellica 1500 Automated Urinalysis System in the Evaluation of Glomerular Hematuria [0.03%]
Yongjung Park,Beom Jin Lim,John Hoon Rim et al.
Yongjung Park et al.
Context.—: Dysmorphic red blood cells (dRBCs) in urine are useful noninvasive markers for distinguishing glomerular hematuria. Objective.—: ...
Claudin 18.2 Expression Concordance in Paired Cytology and Surgical Specimens of Gastric and Gastroesophageal Junction Adenocarcinomas [0.03%]
Ruimeng Yang,Harsimar Kaur,Minhua Wang et al.
Ruimeng Yang et al.
Context.—: Claudin 18.2 (CLDN18.2) is a clinically actionable target in gastric and gastroesophageal junction adenocarcinomas, with patient selection guided by CLDN18.2 immunohistochemistry assay. While surgical specimen...
Reassessing Ferritin Levels in Healthy Older Adults: Updated Reference Ranges and Associated Health Outcomes [0.03%]
Sultana Monira Hussain,John K Olynyk,Hans G Schneider et al.
Sultana Monira Hussain et al.
Context.—: Ferritin is used as a biomarker for iron storage, but levels vary significantly among individuals. Objective.—: To define ...
Temperature-Dependent Long-term and Short-term Stability of Human Epidermal Growth Factor 2 Antigenicity on Pathology Slides [0.03%]
Liam Scott,Julia Benanto,Charles J Robbins et al.
Liam Scott et al.
Context.—: Immunohistochemistry-based assessment of human epidermal growth factor receptor 2 (HER2) is increasingly useful for clinical decision-making in breast, gastroesophageal, and other cancers. Retroactive use of c...
Computer-Aided Quantitative Image Analysis of Multiple Human Epidermal Growth Factor Receptor 2 Immunohistochemistry Assays in Breast Carcinoma [0.03%]
Mélissande Cossutta,Birgit Truumees,Alexandre Papine et al.
Mélissande Cossutta et al.
Context.—: Quantitative image analysis (QIA) is increasingly applied for immunohistochemistry (IHC)-based biomarker assessment in pathology. With the introduction of drugs targeting breast carcinomas (BCs) with low human...
Mast Cell Activation Syndrome: Quantification of Mast Cells Across Conditions Reveals Limited Diagnostic Utility of Mast Cell Counts and Tryptase Depletion Index [0.03%]
Christoph Geisenberger,Solveig Kuss,Hans-Peter Horny et al.
Christoph Geisenberger et al.
Context.—: Mast cell enumeration in gastrointestinal biopsies is commonly requested to diagnose mast cell activation syndrome (MCAS) or systemic mastocytosis (SM) with gastrointestinal (GI) involvement. However, mast cel...
Madhumita Das,Argha Baruah
Madhumita Das
Context.—: Accurate evaluation of calcium status is essential in critically ill patients. However, reliance on total calcium (tCa) and albumin-corrected calcium often leads to misclassification, influencing clinical deci...
Highly Skewed Immunohistochemical αβ:γδ Ratios for T-Cell Receptors Can Be Detected in Reactive Duodenal Biopsies [0.03%]
高度偏斜的免疫组化αβ：γδT细胞受体比率可以被检测为反应性十二指肠活检中的指标
George C de Castro,Gregory R Bean,Kwun Wah Wen
George C de Castro
Context.—: T-cell receptors (TCRs) are classified as αβ- and γδ-chain groups. T-cell lymphoma (TCL) has been shown to express either αβ or γδ TCRs. Immunohistochemical stains for TCR-BetaF1 (TCR-BF1) (αβ) and T...
The Doctor's Doctor Is the Patient's Doctor: A Pilot Quality Improvement Study on Patient-Pathologist Consultations at a Single Institution [0.03%]
医师的医生也是患者的医生：单中心关于病理学家与患者面谈的质量改进研究试点工作
Katherine Drews-Elger,Merce Jorda,Melissa Stedman et al.
Katherine Drews-Elger et al.
Context.—: Pathologists have traditionally worked behind the scenes, providing diagnostic information to clinicians. The 21st Century Cures Act grants patients immediate access to pathology reports, creating opportunitie...