KMT2A Amplification in Mixed-Phenotype Acute Leukemia: Immunophenotyping, Cytogenomic Features, and Clinical Correlation
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Context.—: Mixed-phenotype acute leukemia (MPAL) is a rare form of leukemia with a typically unfavorable prognosis. While KMT2A (lysine methyltransferase 2A) rearrangements resulting in gene fusions are common in MPAL, informati... ...