Stephen R Reeves,Charles W Frevert
Stephen R Reeves
Goblet Cells Signaling to the Alveolar Niche: Macrophages Are the Link [0.03%]
杯状细胞与肺泡微环境之间的信号转导：巨噬细胞是其关键联系单元
A Scott McCall,Jason J Gokey
A Scott McCall
From Splicing Landscape to Therapeutic Targets: Long-Read Sequencing in Non-Small-Cell Lung Cancer [0.03%]
从基因拼接景观到治疗靶点：长读测序在非小细胞肺癌中的应用
Wei Chen,Pedro L Baldoni,Anny Xiaobo Zhou
Wei Chen
CSF-1 Receptor Blockade in Pulmonary Arterial Hypertension - Keeping Macrophages in Check? [0.03%]
肺动脉高压中的CSF-1受体阻断——让巨噬细胞保持稳定？
Marija Gredic,Norbert Weissmann
Marija Gredic
IRAK2 Ubiquitination Mediated by PELI1 Impairs Airway Epithelial Function and Accelerates Pediatric Asthma [0.03%]
由PELI1介导的IRAK2泛素化损害气道上皮功能并加速儿童哮喘进展
Sha Wang,Jinping Ruan,Pan Yan et al.
Sha Wang et al.
PELI1, an E3 ubiquitin ligase, has been identified as a controller of the innate immune response. This study was designed to expound the functional role of PELI1 in asthma (AS). Newborn mice were induced with house dust mite (HDM) to establ...
Fortilin Binds IRE1β to Facilitate Mucin 5AC Expression via the IRE1β/XBP1 Signaling Pathway [0.03%]
Fortilin通过IRE1β/XBP1信号通路结合IRE1β促进黏蛋白MUC5AC表达
Decha Pinkaew,Uttariya Pal,Ken Fujise et al.
Decha Pinkaew et al.
Airway mucus is a complex process influenced by various factors and signaling pathways. A key player is mammalian inositol-requiring enzyme 1 beta (IRE1β), a paralog of IRE1 alpha (IRE1α), found only in epithelial cells lining the mucosal...
Targeting CSF1R Attenuates the Development of Pulmonary Arterial Hypertension through CCL2 [0.03%]
靶向CSF1R通过CCL2减轻肺动脉高压的发展
Kazuto Nishiura,Tetsuro Yokokawa,Shohei Ichimura et al.
Kazuto Nishiura et al.
Pulmonary arterial hypertension (PAH) is a progressive disease characterized by elevated pulmonary arterial pressure and right ventricular failure. The perivascular macrophages in the lungs play a crucial role in the development of PAH. Her...
The NADPH Oxidase DUOX1 Contributes to Profibrotic Macrophage Activation and Pulmonary Fibrosis [0.03%]
NADPH氧化酶DUOX1参与促纤维化巨噬细胞活化和肺纤维化的作用机制研究
Aida Habibovic,Miao-Chong Lin,Carolyn R Morris et al.
Aida Habibovic et al.
Fibrotic lung diseases such as idiopathic pulmonary fibrosis (IPF) are caused by various forms of environmental injury and involve reciprocal interactions between activated (myo)fibroblasts and recruited monocyte-derived macrophages (MoMacs...