Pirfenidone and its Derivative: Novel Bronchodilators and Leukocyte Airway Inflammation Inhibitors
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Asthma, a chronic airway inflammatory disease, manifests as excessive obstruction of the airways and airway hyperresponsiveness (AHR) due to airway smooth muscle (ASM) contraction. Conventional bronchodilator treatments, such as β2-adrenergic receptor (β2-AR... ...