Rumeal D Whaley,Sounak Gupta,Lori A Erickson
Rumeal D Whaley
The challenging aspect of adrenal gland pathology is that adrenal cortical carcinoma is rare but is in the differential for every adrenal gland biopsy and adrenalectomy specimen. Currently, the Weiss system (for adult patients) and Wieneke ...
Ajay Rajaram,Pierre Olivier Fiset,Fadi Brimo
Ajay Rajaram
Mesothelial lesions of the testis and paratestis encompass a spectrum of reactive, benign, and malignant processes that may overlap morphologically with one another and with other intra- and extratesticular neoplasms, including Müllerian-t...
TFE-Altered Renal Cell Carcinoma: A Contemporary Review With Practical Insights and Diagnostic Pearls for Surgical Pathologists [0.03%]
肾细胞癌中的TFE改变：实用见解和诊断要点的当代综述（外科病理学家专用）
Christopher G Przybycin,Jane K Nguyen,Reza Alaghehbandan
Christopher G Przybycin
Since the initial recognition of unique renal cell carcinomas (RCC) with the ASPCR1::TFE3 gene fusion, the category of MiT-family RCC has evolved to include TFE3-rearranged RCC, TFEB-rearranged RCC, and TFEB-amplified RCC, 3 entities with s...
Hongzhi Xu,Jasreman Dhillon
Hongzhi Xu
Intraepithelial penile lesions encompass non-neoplastic and preneoplastic lesions. Non-neoplastic lesions comprise condyloma acuminatum, including giant condyloma acuminatum, also known as Buschke-Löwenstein tumor. It is usually the low-ri...
Akash Pramod Sali,Santosh Menon
Akash Pramod Sali
Penile squamous cell carcinomas (pSCC) are broadly divided into two subgroups based on their etiopathogenesis: Human Papillomavirus (HPV)-associated and HPV-independent. HPV-associated pSCC is driven by high-risk HPV and commonly overexpres...
Doaa Alqaidy,Mylene T Truong,Cesar A Moran
Doaa Alqaidy
The occurrence of spindle cell tumors of the pleural other than the conventional sarcomatoid mesothelioma or solitary fibrous tumor, is rather unusual. Clinically and radiologically, patients with these tumors may show similar features as t...
Hyun-Soo Kim,Esther Oliva,Gulisa Turashvili
Hyun-Soo Kim
DICER1 plays a crucial role in the biogenesis and maturation of microRNAs. Germline mutations in the DICER1 gene are associated with an increased risk of developing a wide range of benign and malignant neoplasms. The same tumors may also ar...
Pedram Argani,Cristina R Antonescu
Pedram Argani
In 1952, Christopherson and colleagues described the distinctive clinical and pathologic features of alveolar soft part sarcoma (ASPS). For nearly half a century, controversy raged regarding the putative cell of origin of this peculiar neop...
Evolving Concepts in Liver Pathology (Part II): Application to Interpretation of Medical Liver Biopsies [0.03%]
肝脏病理学的概念演变（第二部分）：在医学肝活检解释中的应用
Hanlin L Wang,Romil Saxena
Hanlin L Wang
Perivascular Cell Tumors (PEComas) of the Genitourinary Tract: A Summary [0.03%]
泌尿生殖道血管周上皮样细胞肿瘤(PEComas)概论
Susan K Potterveld,Pedram Argani,Ankur R Sangoi
Susan K Potterveld
Perivascular cell tumors (PEComas) in the genitourinary tract have an overwhelming propensity to occur in the kidney, where they are synonymously referred to as angiomyolipomas (AMLs). Although less common, PEComas may occur throughout the ...