The Role of the Surgical Pathologist in the Recognition of Hereditary SDH-Deficient Tumor Syndromes
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Succinate dehydrogenase (SDH)-deficient tumors form an expanding, clinically important group of neoplasms driven by disruption of mitochondrial complex II through germline or somatic alterations in SDHA-D or SDHAF2, or by epigenetic silencing within the pathwa... ...