Sarcomatoid carcinoma of the prostate - A single institution experience with emphasis on molecular genetic findings [0.03%]
前列腺肉瘤样癌的单机构经验及分子遗传学特征强调
Burak Tekin,Lagnajita Datta,Ramin Zargham et al.
Burak Tekin et al.
Objectives: Sarcomatoid carcinoma of the prostate (SCP) is a rare neoplasm known for its diagnostic difficulties and aggressive clinical course. Given the paucity of literature on its molecular landscape, we aimed to inve...
Impact of Gender and Age on the Histologic Severity of Metabolic Syndrome Associated Steatohepatitis [0.03%]
性别和年龄对代谢性肝病组织学严重程度的影响
Eesha K Acharya,Robert Lam,Joseph K Lim et al.
Eesha K Acharya et al.
Background: Metabolic dysfunction-associated steatotic liver disease (MASLD) and its progressive form, metabolic dysfunction-associated steatohepatitis (MASH), are leading causes of chronic liver disease. Although clinica...
Conventional FLCN-mutated tumor: a retrospective study of 5 cases with emphasis on diagnostic challenges [0.03%]
FLCN突变的5例经典康科德病患者的临床特征及诊断陷阱分析：单中心回顾性研究
Liangbin Wan,Bin Xie,Qi Li et al.
Liangbin Wan et al.
Background: Conventional FLCN-mutated tumors (c-FMTs) occur in Birt-Hogg-Dubé syndrome (BHD), posing diagnostic challenges due to their overlapping histology with chromophobe renal cell carcinoma (ChRCC) and renal oncocy...
Prevalence and Distribution of Human Papillomavirus Type 16 in Esophageal Squamous Cell Carcinoma and Its Association with p16INK4A Expression: A Large-Scale Study in Japan [0.03%]
人乳头瘤病毒16型在日本食管鳞状细胞癌中的流行率、分布及其与p16ink4a表达的关系：一项大规模研究
Kaiyuan Jiang,Hirotaka Ishida,Yusuke Taniyama et al.
Kaiyuan Jiang et al.
The infection rate of human papillomavirus (HPV) in esophageal squamous cell carcinoma (ESCC) varies widely (0%-88.9%), and the diagnostic utility of p16INK4A as a surrogate marker remains controversial. Moreover, the distribution of HPV in...
Integrating computational pathology and multi-transcriptomics to characterize glioblastoma heterogeneity and identify prognostic biomarkers [0.03%]
计算病理学和多转录组的融合用于胶质母细胞瘤异质性表征及预后生物标志物的鉴定
Ying Dai,Chenglong Shi,Kai Zhao et al.
Ying Dai et al.
Background: Glioblastoma (GBM) remains a lethal brain cancer with median survival of 12-15 months, hindered by pronounced heterogeneity. Integrating histopathological, molecular, and microenvironmental data is critical fo...
EWSR1-and FUS-rearranged acute leukemias: Clinicopathological and genomic characterization [0.03%]
EWSR1和FUS重排的急性白血病：临床病理和基因组特征分析
Van Tuong Nguyen,Mohammad Faizan Zahid,Lina Han et al.
Van Tuong Nguyen et al.
Background: EWSR1::FEV and FUS::FEV fusions, belonging to the FET-ETS family gene fusions, are extremely rare in acute leukemias. Our study aims to characterize the clinicopathologic and genomic profiles of this rare enti...
Cytopathologic and histopathologic characteristics of SMARCB1 deficient neoplasm and correlation with molecular and immunohistochemical findings [0.03%]
SMARCB1缺失肿瘤的细胞病理和组织病理特征及其与分子及免疫组化发现的相关性
Sandra Ixchel Sanchez,Christina Adams,Peter Illei et al.
Sandra Ixchel Sanchez et al.
Introduction: SMARCB1 deficient neoplasm is an aggressive and heterogeneous group of neoplasms. The morphology of the neoplasm is highly variable. Recent clinical trials show that targeted therapy with EHZ2 inhibitor taze...
Histomorphological and molecular spectrum of ciliated muconodular papillary tumors with implication for malignant potential: Insights from a literature review and series report [0.03%]
纤毛黏黏膜乳头状肿瘤的临床病理和分子谱系及其恶性潜能的意义：文献回顾及病例系列报告
Jieyu Wu,Xina Lin,Dazhou Li et al.
Jieyu Wu et al.
Although the lung ciliated muconodular papillary tumor (CMPT) is defined as a benign tumor by the 5th WHO classification, recent studies have shown that its morphology and genetic alteration may indicate it has undetermined malignant potent...
Myoepithelial and Epithelial-myoepithelial Clinically Advanced and Metastatic Carcinomas of Salivary Gland: A Comparative Comprehensive Genomic Profiling Study [0.03%]
唾液腺肌上皮瘤和上皮肌上皮瘤的临床进展期及转移性癌的全面基因组分析研究
Céline S C Hardy,Kevin M Lin,Dean Pavlick et al.
Céline S C Hardy et al.
Myoepithelial carcinoma (MECA) and Epithelial-myoepithelial carcinomas (EMC) are rare salivary gland carcinomas (SGCA) that may arise de novo or in the background of a prior pleomorphic adenoma (carcinoma ex pleomorphic adenoma CAEXPLA). De...
HPV-related Multiphenotypic Sinonasal Carcinoma: Clinicopathologic and Immunohistochemical Characterization of 3 Cases with Comprehensive Literature Review and Emphasis on Differential Diagnosis [0.03%]
与HPV相关的多表型鼻腔和鼻窦癌：3例临床病理及免疫组化特征分析，结合全面文献回顾及强调鉴别诊断
Gabriella C Speakman,Paul E Wakely Jr,Prokopios P Argyris
Gabriella C Speakman
HPV-related multiphenotypic sinonasal carcinoma (HMSC) represents a rare malignancy exhibiting surface and salivary gland-derived properties, and a strong association with high-risk HPV. We present the clinicopathologic and immunohistochemi...