Clinicopathological significance and prognostic impact of perineural invasion in intrahepatic cholangiocarcinoma: a single-center, retrospective study [0.03%]
肝内胆管癌伴癌周神经侵犯的临床病理意义及预后影响：单中心回顾性研究
Shota Kami,Motohiro Kojima,Masashi Kudo et al.
Shota Kami et al.
Perineural invasion (PNI) is a recognized prognostic factor in various malignancies, but its clinical relevance in intrahepatic cholangiocarcinoma (ICC) remains unclear. This retrospective study aimed to evaluate the impact of PNI on clinic...
Non-Invasive Follicular Thyroid Neoplasm with Papillary-Like Nuclear Features (NIFTP) in the Adolescent and Young Adult Population: A Pediatric Center Experience [0.03%]
青少年和年轻人的类乳头状核特征非侵袭性滤泡甲状腺肿瘤(NIFTP)一儿科中心经验报告
Mariel Bedell,John M Skaugen,Yuri Nikiforov et al.
Mariel Bedell et al.
Non-invasive follicular thyroid neoplasm with papillary-like nuclear features (NIFTP) is a well-demarcated tumor with follicular growth pattern and papillary thyroid carcinoma-like nuclear features. Only rare reports exist in the literature...
Insights from Single Cell and Bulk RNA Sequencing: Increased NOTCH Signaling is Correlated with Oncogenic Transformation of Juxtaglomerular Cells to Juxtaglomerular Cell Tumors [0.03%]
单细胞和批量RNA测序的见解：NOTCH信号增加与球旁细胞向球旁细胞肿瘤癌变的相关性
Sounak Gupta,Surendra Dasari,Wei Shen et al.
Sounak Gupta et al.
Renin-expressing juxtaglomerular cells in the kidney are the cell of origin for rare juxtaglomerular cell tumors, and affected patients often experience prolonged diagnostic odysseys as they present with relatively nonspecific symptoms rela...
Evaluation of nuclear pseudoinclusions, GATA3, 34βE12, and GPNMB performances in CK7 diffuse positive clear cell renal cell neoplasms [0.03%]
CK7弥散阳性透明细胞肾细胞肿瘤核假包涵体、GATA3、34βE12和GPNMB评估
Meihua Chen,Yang Liu,Yuankai Wu et al.
Meihua Chen et al.
Recent studies have revealed histological diversity among clear cell renal cell neoplasms demonstrating diffuse CK7 positivity. While prior research established the utility of GATA3 and 34βE12 immunohistochemistry in clear cell papillary r...
Niklas Sarelin,Valtteri Kairaluoma,Juha Saarnio et al.
Niklas Sarelin et al.
Objectives: Prior studies have suggested a link between tumour budding and poor prognosis in hepatocellular carcinoma (HCC), while the prognostic value of tumour-stroma ratio (TSR) remains unclear. This study assessed the...
GNAQ-/GNA14-mutated Hepatic Vascular Malformation with Capillary Proliferation in Adults and Children [0.03%]
成人和儿童中毛细血管增生的肝血管畸形伴GNAQ/GNA11基因突变
Anne Kristin Fischer,Carina Heydt,Janna Siemanowski-Hrach et al.
Anne Kristin Fischer et al.
Aims: Congenital hepatic vascular malformation with capillary proliferation (HVMCP) is a rare pseudo-tumourous liver lesion, to date only known in children. Diagnostic pitfalls in infant and, for the first time, in adult ...
CTNNB1 mutations in serum amyloid A-positive hepatocellular neoplasm/inflammatory hepatocellular adenoma arising in alcoholic cirrhosis [0.03%]
酒精性肝硬化伴发的血清淀粉样A阳性肝细胞肿瘤/炎性肝细胞腺瘤中的CTNNB1基因突变
Motoko Sasaki,Yasunori Sato,Yasuni Nakanuma
Motoko Sasaki
Background: Serum amyloid A-positive hepatocellular neoplasm (SAA-HN) arising in alcoholic cirrhosis is now regarded as a specific type of inflammatory hepatocellular adenoma (IHCA) associated with advanced liver disease....
Undifferentiated Embryonal Sarcoma of the Liver: A Clinicopathological and Genomic Study of 10 Cases from a Single Institution [0.03%]
肝未分化胚胎性肉瘤的临床病理和基因组特征研究（10例报告）
Paul Zamiara,Nick Shillingford,Larry L Wang et al.
Paul Zamiara et al.
Aims: Undifferentiated embryonal sarcoma of the liver (UESL) is a rare and aggressive malignancy with limited clinicopathological and genomic characterization. This study aimed to investigate the genomic abnormalities in ...
Clinicopathological characteristics and immune infiltration analysis of esophagogastric junction adenocarcinoma with alterations in SWI/SNF complex [0.03%]
SWI/SNF复合体突变的食管胃交界部腺癌的临床病理特点及免疫浸润分析
Na Cheng,Bingzhi Wang,Jiaqi Xu et al.
Na Cheng et al.
Background: Alterations in SWI/SNF complex were mostly detected in poorly differentiated or undifferentiated gastric/esophagogastric junction adenocarcinoma (EGJA). However, there was a lack of studies investigating these...
Interdisciplinary Analysis of Cues to Triage Gastric Lymphoid Proliferations: Role of the Surgical Pathologist Revisited [0.03%]
胃淋巴增生性病变分流的跨学科分析：重温外科病理学家的作用
Radhika Sekhri,Xuejun Tian,Jiani Chai et al.
Radhika Sekhri et al.
Surgical pathologists who examine gastric biopsies must triage exuberant lymphoid infiltrates for hematopathology consultation, a task that should account for resource and time utilization. We assembled all cases of chronic gastritis sent b...