Ann-Kathrin Eisfeld,L Jeffrey Medeiros
Ann-Kathrin Eisfeld
Myeloid sarcoma is defined as a neoplasm of myeloid blasts that involves an extramedullary site as a mass and effaces tissue architecture. Myeloid sarcoma is considered clinically to be equivalent to acute myeloid leukemia (AML) and require...
Pathologic Characterization of Non-Mass Enhancement Lesions of the Breast in MRI-guided Biopsy [0.03%]
乳腺磁共振引导下活检非肿块增强病变的病理学特征分析
Tristan Jordan,Yuanxin Liang,Lorraine Colón Cartagena et al.
Tristan Jordan et al.
Objective: Breast MRI is widely used for screening high-risk patients and for assessing the extent of disease in patients with breast cancer. The goal of this study was to determine the pathologic findings associated with...
Nonconventional Colorectal Dysplasia Is Less Prevalent and Has a More Limited Morphologic Spectrum in Patients Without Inflammatory Bowel Disease [0.03%]
非克罗恩病患者的非典型结直肠不规则上皮病变发生率低且形态表现有限
Timothy Law,Dongliang Wang,Gregory Y Lauwers et al.
Timothy Law et al.
Colorectal dysplasia in inflammatory bowel disease (IBD) includes conventional and diverse nonconventional morphologic patterns, the latter of which are often endoscopically invisible or flat and are associated with an increased risk of adv...
SMARCA4-Altered Malignancies: Cytologic Diagnostic Challenges and Clinicopathologic Correlates [0.03%]
SMARCA4异常恶性肿瘤的细胞学诊断挑战及临床病理特征相关性研究
Behtash G Nezami,Qiuying Shi,Xiaoqi Lin
Behtash G Nezami
Background: SMARCA4-deficient undifferentiated tumors (SMARCA4-dUT) have been included in the latest WHO classification of tumors. This study examined the cytomorphology, management, molecular features and prognosis of ma...
ERBB2 Copy Number Alterations and Protein Expression in Bladder Cancer Treated by Cystectomy [0.03%]
接受膀胱切除术的膀胱尿路上皮癌中ERBB2拷贝数变异及蛋白表达特点分析
John C Cheville,Burak Tekin,Jacob J Orme et al.
John C Cheville et al.
The introduction of antibody-drug-conjugates (ADC) that target HER2 has renewed interest in ERBB2 alterations in bladder cancer. Little is known about the frequency of ERBB2 copy number alterations in primary bladder cancer subtypes and reg...
Molecular Subtypes and Genetic Diagnostics in B-cell Acute Lymphoblastic Leukemia [0.03%]
B细胞急性淋巴细胞白血病的分子分型和遗传诊断
Roberta S Azevedo,L Jeffrey Medeiros,Sanam Loghavi et al.
Roberta S Azevedo et al.
The molecular classification of B-cell acute lymphoblastic leukemia (B-ALL) has evolved substantially with the introduction of genome-wide technologies for diagnosis, leading to the recognition of numerous genetic subtypes with distinct bio...
Single-section assessment of DNA mismatch repair using PMS2/MSH6 double immunohistochemistry [0.03%]
联合使用PMS2/MSH6双免疫组化检测DNA错配修复蛋白单一蛋白缺陷
Yuichiro Hatano,Kohei Taniguchi,Akihiko Toji et al.
Yuichiro Hatano et al.
This retrospective diagnostic concordance study evaluated the feasibility and performance of PMS2/MSH6 double immunohistochemistry (DIHC) as a single-section screening tool for deficient mismatch repair (dMMR). The study was conducted at a ...
Metastatic pancreatic acinar cell carcinoma to the liver mimicking neuroendocrine tumor (NET) and pancreatic ductal adenocarcinoma (PDAC): A series of seven cases [0.03%]
类似神经内分泌肿瘤和胰腺导管腺癌的肝转移性胰腺胞膜细胞癌：七例报告系列
Tiane Chen,Ralph H Hruban,Pedram Argani
Tiane Chen
Acinar cell carcinomas (ACCs) of the pancreas typically demonstrate distinct morphologic features including minimal fibrous stroma, acinar architecture, relative nuclear uniformity, single prominent nucleoli and eosinophilic cytoplasmic gra...
Clinicopathologic and Histologic Determinants of the Oncotype DX Recurrence Score in ER+/HER2- Breast Cancer: AJCC Stage-Matched Comparisons and Predictors of a Very Low Recurrence Score [0.03%]
ER阳性且HER2阴性乳腺癌中OncoTypeDX复发评分的临床病理和组织学决定因素：AJCC分期匹配比较及低危基因表达模式的预后意义
Zohre Sadeghian,Sara Rhode,Hadi Sultan et al.
Zohre Sadeghian et al.
Context: The Oncotype DX Recurrence Score (RS) is used to guide adjuvant chemotherapy decisions in estrogen receptor-positive (ER+), human epidermal growth factor receptor 2-negative (HER2-) early breast cancer. Although ...
Sanam Loghavi,L Jeffrey Medeiros
Sanam Loghavi