Eleanor A Medley,Emma Spring,Mia Charifson et al.
Eleanor A Medley et al.
Introduction: Placental development, involving rapid vascularization, is regulated by concentration gradients of numerous growth factors and hormones. Placental growth factor (PlGF) promotes vasculogenesis and angiogenesi...
Lymphatic mimicry of spiral arteries is impaired by human sFLT1 overexpression in a preeclampsia mouse model [0.03%]
Alina Edinger,Charlotte Cathrin Mohr,Elisa Marie Elfroth et al.
Alina Edinger et al.
Introduction: The pregnancy disorder preeclampsia (PE) is characterized by maternal hypertension and reduced spiral artery (SpA) remodeling which is aggravated by increased levels of anti-angiogenic soluble fms-related ty...
Influence of SARS-CoV-2 variants on stillbirth rate - data from the CRONOS registry [0.03%]
SARS-CoV-2变异对死胎率的影响——来自CRONOS注册中心的数据
Nora Schaumann,Nadine Mand,Tanja Groten et al.
Nora Schaumann et al.
Background: During the COVID-19 pandemic, reports of stillbirths associated with SARS-CoV-2 infection increased. This study aims to assess whether and to what extent these stillbirths are associated with placental changes...
Effect of circulating small extracellular vesicles isolated from recurrent pregnancy loss (RPL) women and normal pregnant women on decidualization [0.03%]
复发性妊娠丢失患者和正常孕妇血循环中小胞外囊泡对蜕膜化的影响研究
Kanika Aggarwal,Shivi Khurana,Unnati Sharma et al.
Kanika Aggarwal et al.
Introduction: Studies have demonstrated a correlation between recurrent pregnancy loss (RPL) and anomalies in the decidualization process. The aim of this study was to explore whether circulating small extracellular vesic...
Stefan M Botha,Lucy A Bartho,Sunhild Hartmann et al.
Stefan M Botha et al.
Introduction: Preeclampsia involves endothelial dysfunction and impaired angiogenesis. Thrombospondin-1 (THBS1), a pro-thrombotic and anti-angiogenic glycoprotein, may contribute to preeclampsia pathogenesis. This study i...
Natural-killer-cell-dominant immune landscape and HLA-E-mediated immune evasion in choriocarcinoma [0.03%]
绒癌以自然杀伤细胞为主的免疫图谱及其人白细胞抗原-E介导的免疫逃逸机制
Mayu Shibata,Kosuke Yoshida,Yuko Yasui et al.
Mayu Shibata et al.
Objective: Choriocarcinoma is a rare cancer associated with antecedent pregnancy. Therefore, its development may be influenced by an immune-evasive tumor microenvironment. In this study, we focused on natural killer (NK) ...
John Aplin
John Aplin
Impaired placental vascular remodeling and persistent uNK cells in the RUPP model: A time-dependent perspective [0.03%]
RUPP模型胎盘血管重塑障碍及uNK细胞持续存在：时间依赖性视角
C M van Kammen,F M Al Darwish,G J Strijkers et al.
C M van Kammen et al.
Background: Placental insufficiency underlies major obstetric complications such as preeclampsia and fetal growth restriction (FGR). The reduced uterine perfusion pressure (RUPP) model is widely used to mimic PE and FGR; ...
Placental nutrient transporter abundance in gestational diabetes mellitus with normal birthweight [0.03%]
正常体重妊娠期糖尿病患者的胎盘营养转运蛋白含量研究
Pradhiki Mahindra,Sara L Hillman,Dimitrios Siassakos et al.
Pradhiki Mahindra et al.
Introduction: Gestational diabetes mellitus (GDM) is associated with adverse pregnancy outcomes. When the infant is large for gestational age, placental nutrient transport capacity is often increased. We hypothesized that...
miR-196a-5p suppresses the MAPK/ERK pathway by targeting HOXA7 to regulate the proliferation and apoptosis of placental trophoblasts in gestational diabetes [0.03%]
miR-196a-5p通过靶向HOXA7抑制MAPK/ERK途径以调控妊娠糖尿病胎盘滋养细胞的增殖和凋亡
Jianhua Li,Xinping Xie,Lin Lu et al.
Jianhua Li et al.
Introduction: Gestational diabetes mellitus (GDM) disrupts placental trophoblast function through hyperglycemia-induced apoptosis and impaired proliferation. Non-coding RNAs, particularly miR-196a-5p, are implicated in GD...