Prognostic Value of a Novel Nuclear Grading of Cutaneous Melanoma: The UNC Chapel Hill Method [0.03%]
一种新的皮肤黑色素瘤细胞核分级方法(UNC教堂山法)的预后价值
Sarah G McAlpine,Shantanu Srivatsa,Paige C Jones et al.
Sarah G McAlpine et al.
We developed a nuclear grading system for melanoma, the UNC Chapel Hill Method, akin to McGovern's 1970 classification, to evaluate its correlation with disease progression and adverse histologic features, including thickness, mitotic rate,...
Nonvisceral YAP1::TFE3-Rearranged Inflammatory Spindle Cell PEComa in Somatic Soft Tissue: Clinicopathologic and Molecular Analysis of 3 Cases [0.03%]
3例发生于躯干软组织的非 visceral YAP1-TFE3 易位炎性梭形细胞 PEComa 的临床病理及分子分析
Abdalla Malik,Gloria Zhang,Karen Fritchie et al.
Abdalla Malik et al.
Inflammatory spindle cell PEComa is a rare PEComa variant with rare cases harboring YAP1::TFE3 fusion recently reported in the lungs. These tumors share identical YAP1::TFE3 fusion breakpoints and overlapping morphology with clear cell stro...
Crypt Dysplasia is a Risk Factor for the Development of High-Grade Dysplasia/Adenocarcinoma in Barrett Esophagus [0.03%]
隐窝发育不良是巴雷特食管高分级上皮内瘤变/腺癌发病的风险因素
Vikram Deshpande,Melissa Zhao,Azfar Neyaz et al.
Vikram Deshpande et al.
The aim of this study was to perform a detailed clinical and pathologic analysis of biopsies from 180 BE patients with the goal of understanding the clinical significance and outcome of patients diagnosed with crypt dysplasia (CD). Biopsies...
Cyclin D1 Overexpression With Cytoplasmic Localization Distinguishes Erdheim-Chester Disease From Reactive Histiocytic Infiltrates [0.03%]
cyclinD1过度表达及胞浆定位可将 Erdheim-Chester病与反应性组织细胞浸润相区分
Alma R Oskarsdottir,Aishwarya Ravindran,Matthew J Koster et al.
Alma R Oskarsdottir et al.
Erdheim-Chester disease (ECD) is a rare disease characterized by the accumulation of neoplastic histiocytes in various extra-nodal tissues. Tissue biopsies involved by ECD are difficult to distinguish from reactive inflammatory infiltrates ...
Clinicopathologic Analysis of 34 Japanese Patients With EBV-Associated Reactive Lymphoid Hyperplasias [0.03%]
34例日本EB病毒相关反应性淋巴结增生患者的临床病理分析
Yuuki Yamamoto,Akira Satou,Taishi Takahara et al.
Yuuki Yamamoto et al.
The 5th edition of the WHO classification of haematolymphoid tumours introduces the concept of hyperplasias arising in immune deficiency and dysregulation (IDD), which are frequently associated with Epstein-Barr virus (EBV). These lesions c...
Primary Uterine Nongestational Placental Site Trophoblastic Tumor as a Distinct Entity: A Report of 5 Cases [0.03%]
原发性子宫非妊娠胎盘部位滋养细胞肿瘤作为一个独立实体的报告——五例报道及文献回顾
Alexis Trecourt,Geoffrey J Maher,Rosemary A Fisher et al.
Alexis Trecourt et al.
Uterine placental site trophoblastic tumors (PSTTs) are rare trophoblastic neoplasms, presumed to be of gestational origin. Herein, using a comprehensive morphologic, immunohistochemical, and molecular approach, we describe 5 cases of prima...
A Deeper Dive into POLE-Mutated Endometrial Carcinomas: The Contributions and Consequences of Tumor Mutational Burden [0.03%]
POLE突变型子宫内膜癌的进一步探索:肿瘤突变负荷的影响及后果
Anusha Vemuri,Melissa Y Tjota,Pankhuri Wanjari et al.
Anusha Vemuri et al.
POLE-mutated endometrial carcinomas (POLEmut EC) have the most favorable prognosis among all TCGA molecular subgroups. Though the consequent "ultramutated" phenotype is recognized as a trademark feature, hypermutated tumors (10-100 mutation...
Pseudoneoplastic Fat Atrophy of Intra-Abdominal Sites: A Clinicopathologic Study of 16 Cases Representing a Potential Diagnostic Pitfall [0.03%]
腹腔内类新生物性脂肪萎缩的临床病理学研究:16例报告及对诊断的思考
David I Suster,John M Gross,Michael Kallen et al.
David I Suster et al.
Patients undergoing periods of starvation or malnutrition may develop degenerative and/or atrophic changes of various organs. These findings may manifest histologically and may cause confusion when first encountered, raising a differential ...
Fite Staining in Silicone Granulomas: A Previously Unreported Diagnostic Pitfall and Potential Diagnostic Aid [0.03%]
硅胶肉芽肿中的假脂肪染色:一个此前未被报道的诊断陷阱和潜在诊断线索
Kelly J Butnor,Rangsinee Nusapan,Alexa Buskey et al.
Kelly J Butnor et al.
Silicone granulomas can have histologic features that mimic xanthogranulomatous inflammation, particularly in small samples or when the diagnosis is unsuspected. Histochemical stains for microorganisms may be performed to assess for infecti...
Clinicopathologic and Whole Exome Sequencing Analyses of High-Grade Serous Carcinoma-Like Carcinoma of the Breast Reveal Unique Genetic Profile and Poor Clinical Outcome: Erratum [0.03%]
高级别浆液性 carcinoma-like乳腺癌的临床病理及外显子组测序分析显示独特的遗传谱型和不良的临床结局:勘误表
Wen-Yu Hsiao,Thi Truc Anh Nguyen,Wei Yang et al.
Wen-Yu Hsiao et al.