A Deeper Dive into POLE-Mutated Endometrial Carcinomas: The Contributions and Consequences of Tumor Mutational Burden
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POLE-mutated endometrial carcinomas (POLEmut EC) have the most favorable prognosis among all TCGA molecular subgroups. Though the consequent "ultramutated" phenotype is recognized as a trademark feature, hypermutated tumors (10-100 mutations/megabase), as we... ...
