Reply to: Comment on: A Transatlantic Viewpoint on the Role of Pallidal Stimulation for Parkinson's Disease [0.03%]
有关《帕金森病丘脑底核刺激疗法的作用的泛 Atlantic观点》一文的回信
Alexandra Boogers,Alfonso Fasano
Alexandra Boogers
Adult-Onset Dystonia and Hypertrophic Cardiomyopathy in Patient with a De Novo 16q12.2q21 Deletion [0.03%]
成人发作性 dystonia 和肥厚型心肌病患者的新型16号染色体q12.2q21缺失案例报告
Shaochen Qin,Yifeng Li,Yanjing Li et al.
Shaochen Qin et al.
Detecting Misfolded α-Synuclein in Blood Years before the Diagnosis of Parkinson's Disease [0.03%]
帕金森病诊断前几年血液中错误折叠的α-突触核蛋白的检测
Annika Kluge,Eva Schaeffer,Josina Bunk et al.
Annika Kluge et al.
Background: Identifying individuals with Parkinson's disease (PD) already in the prodromal phase of the disease has become a priority objective for opening a window for early disease-modifying therapies. ...
Long-Term Globus Pallidus Internus Deep Brain Stimulation in Pediatric Non-Degenerative Dystonia: A Cohort Study and a Meta-Analysis [0.03%]
儿童非变性 dystonia 进行长期苍白球 internus 深部脑刺激：一项队列研究和荟萃分析
Valentina Duga,Riccardo Giossi,Luigi Michele Romito et al.
Valentina Duga et al.
Background: The evidence in the effectiveness of deep brain stimulation in children with medication-refractory non-degenerative monogenic dystonia is heterogeneous and long-term results are sparse. ...
Localized Changes in Dentate Nucleus Shape and Magnetic Susceptibility in Friedreich Ataxia [0.03%]
弗里德赖希共济失调患者齿状核形态和磁敏感性的局部变化
Ian H Harding,Muhammad Ikhsan Nur Karim,Louisa P Selvadurai et al.
Ian H Harding et al.
Background: The dentate nuclei of the cerebellum are key sites of neuropathology in Friedreich ataxia (FRDA). Reduced dentate nucleus volume and increased mean magnetic susceptibility, a proxy of iron concentration, have ...
Long-Term Follow-Up of the LEAP Study: Early Versus Delayed Levodopa in Early Parkinson's Disease [0.03%]
早期帕金森病早期使用与延迟使用左旋多巴的长期随访研究（LEAP研究）
Henrieke L Frequin,Constant V M Verschuur,Sven R Suwijn et al.
Henrieke L Frequin et al.
Background and objective: The Levodopa in EArly Parkinson's disease study showed no effect of earlier versus later levodopa initiation on Parkinson's disease (PD) progression over 80 weeks. We now report the effects over ...
Randomized Controlled Trial
Movement disorders : official journal of the Movement Disorder Society. 2024 Jun;39(6):975-982. DOI:10.1002/mds.29796 2024
Cortical Myoclonus and Complex Paroxysmal Dyskinesias in a Patient with NAA15 Variant [0.03%]
NAA15变异患者的皮质肌阵挛和复杂发作性运动障碍
Elena Freri,Laura Canafoglia,Claudia Ciaccio et al.
Elena Freri et al.
Bilateral Simultaneous Magnetic Resonance-Guided Focused Ultrasound Pallidotomy for Life-Threatening Status Dystonicus [0.03%]
双边磁共振引导聚焦超声丘脑核团毁损治疗危及生命的扭转痉挛状态疗效观察
Vincenzo Levi,Mario Stanziano,Carmela Pinto et al.
Vincenzo Levi et al.
Background: Invasive treatments like radiofrequency stereotactic lesioning or deep brain stimulation of the globus pallidus internus can resolve drug-resistant status dystonicus (SD). However, these open procedures are no...
Yeast Prion Protein Sup35 Initiates α-Synuclein Pathology in Parkinson's Disease [0.03%]
酵母菌丝蛋白Sup35触发帕金森病α-突触核蛋白病理损伤
Youcui Wang,Hui Li,Ning Song et al.
Youcui Wang et al.
Sinus infection of Saccharomyces cerevisiae accelerates the aggregation of α-synuclein (α-syn) in A53T mice, which was caused by prion protein Sup35. Sup35 promotes α-syn aggregation in vitro and in vivo and leads to Parkinson's disease ...