Alkaline Phosphatases as a Potential Source of Variability in Foslevodopa Response: Muscles beyond Pharmacokinetics [0.03%]
碱性磷酸酶可能是福斯左多巴反应变异性的潜在来源：药物动力学之外的肌肉作用
Fabienne Ory-Magne,David Devos,Guillaume Baille
Fabienne Ory-Magne
Reply to: "Alkaline phosphatases as a potential source of variability in foslevodopa response: Muscles beyond pharmacokinetics" [0.03%]
关于“碱性磷酸酶作为富马世伏多巴反应潜在变异性来源：药代动力学之外的肌肉”的回信
Manon Auffret,Marc Vérin
Manon Auffret
Reply to: "Dual Anatomical Targeting or Dual-Target Stimulation in Tremor-Dominant Parkinson's Disease?" [0.03%]
针对震颤为主帕金森病的“双重解剖定位”或“双重靶点刺激”？答复一篇题为“震颤为主帕金森病的双重解剖定位还是双重靶点刺激？”的文章
Zhengyu Lin,Dianyou Li
Zhengyu Lin
Dual Anatomical Targeting or Dual-Target Stimulation in Tremor-Dominant Parkinson's Disease? [0.03%]
震颤为主帕金森病的双重解剖定位靶点刺激吗？
Antonella Macerollo,Jibril Osman Farah
Antonella Macerollo
COVID-19 Amplifies Sex-Specific Dopamine and Glial Responses in a Parkinson's Disease Mouse Model [0.03%]
Covid-19加剧帕金森病小鼠模型中的性别特异性多巴胺和胶质反应
Ifeoluwa Awogbindin,Mélanie Bourque,Marc Morissette et al.
Ifeoluwa Awogbindin et al.
Background: Exposure to environmental agents, including viral infections, may increase Parkinson's disease (PD) susceptibility, especially in males, but the neurodegenerative risk extent of COVID-19 remains uncertain. ...
Early Longitudinal Brain Network Changes in Huntington's Disease Before Clinical Motor Onset [0.03%]
临床运动症状出现前亨廷顿病的大脑连接纵向变化
Michela Leocadi,Nicola Z Hobbs,Mena Farag et al.
Michela Leocadi et al.
Background: Longitudinal studies of seed-based functional connectivity (SBFC) in young adult Huntington's disease gene-expanded (HDGE) individuals are rare, and none, to our knowledge, have examined adult cohorts decades ...
Hasnahana Chetia,Laura Kus,Erika Sipos et al.
Hasnahana Chetia et al.
Background: Spinocerebellar ataxia type 3 (SCA3) is a neurodegenerative disorder caused by an abnormally long polyglutamine-encoding CAG repeat in the ATXN3 gene. ...
Cannabis-Based Oil for Pain and Other Non-Motor Symptoms in Parkinson's Disease: A Randomized Controlled Trial [0.03%]
大麻基油对帕金森病疼痛和其他非运动症状的效果：一项随机对照试验
Gabriel T Kubota,Jacy B Parmera,Matheus Deltreggia et al.
Gabriel T Kubota et al.
Background: There is a lack of treatments for non-motor symptoms (NMS) in Parkinson's disease (PD). Objective: To assess the safety and...
Type 2 α-Synuclein Seed Amplification as a Diagnostic Reassessment Signal in Parkinson's Progression Markers Initiative Parkinson's Disease [0.03%]
Parkinson病进展标志物计划中第2型α-突触核蛋白种子放大作为诊断重新评估信号
Aishanjiang Yusufujiang,Shan Zeng,Hongyan Li
Aishanjiang Yusufujiang
Rare Heterozygous Loss-of-Function Variants in MCOLN1 Identified in Two Sporadic Patients with α-Synucleinopathies [0.03%]
MCOLN1中罕见的杂合功能丧失变异在2例散发性α突触核蛋白病患者中的发现
Chenxin Ying,Xinhui Chen,Zhidong Cen et al.
Chenxin Ying et al.
Background: Growing evidence links lysosomal dysfunction to parkinsonism. TRPML1, a lysosomal cation channel encoded by the MCOLN1 gene, is essential for lysosomal function. Biallelic loss-of-function variants in MCOLN1 c...