Phase 2a Randomized Controlled Trial of TPN-101, A Nucleoside Reverse Transcriptase Inhibitor, in Progressive Supranuclear Palsy
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Background: Preclinical and human brain postmortem studies indicate that progressive supranuclear palsy (PSP) is associated with increased expression of the retrotransposon Long Interspersed Nuclear Element-1 (L1Hs). L1Hs activit... ...
